Objectives Twenty-eight genetic loci are associated with serum urate levels in Europeans.
Evidence for association with gout at most loci is absent, equivocal or not replicated. Our aim
was to test the loci for association with gout meeting the American College of Rheumatology
gout classification criteria in New Zealand European and Polynesian case-control sample
sets. Methods 648 European cases and 1550 controls, and 888 Polynesian (Ma¯ ori and
Pacific) cases and 1095 controls were genotyped. Association with gout was tested by …

Twenty-eight genetic loci are associated with serum urate levels in Europeans. Evidence for
association with gout at most loci is absent, equivocal or not replicated. Our aim was to test
the loci for association with gout meeting the American College of Rheumatology gout
classification criteria in New Zealand European and Polynesian case-control sample sets.
648 European cases and 1550 controls, and 888 Polynesian (Maori and Pacific) cases and
1095 controls were genotyped. Association with gout was tested by logistic regression …