Heterotrimeric G protein complexes are molecular switches relaying extracellular signals
sensed by G protein–coupled receptors (GPCRs) to downstream targets in the cytoplasm,
which effect cellular responses. In the plant heterotrimeric GTPase cycle, GTP hydrolysis,
rather than nucleotide exchange, is the rate-limiting reaction and is accelerated by a
receptor-like regulator of G signaling (RGS) protein. We hypothesized that posttranslational
modification of the Gα subunit in the G protein complex regulates the RGS-dependent …

Heterotrimeric G proteins function in development, biotic, and abiotic stress responses,
hormone signaling as well as sugar sensing. We previously proposed that discrimination of
these various external signals in the G protein pathway is accomplished in plants by
membrane-localized receptor-like kinases (RLKs) rather than G-protein-coupled receptors.
Arabidopsis thaliana Regulator of G Signaling protein 1 (AtRGS1) modulates G protein
activation and is phosphorylated by several RLKs and by WITH-NO-LYSINE kinases …