Unraveling the harmful effect of oxidative stress on male fertility: A mechanistic insight

T Hussain, M Kandeel, E Metwally, G Murtaza… - Frontiers in …, 2023 - frontiersin.org
Male infertility is a widely debated issue that affects males globally. There are several
mechanisms involved. Oxidative stress is accepted to be the main contributing factor, with
sperm quality and quantity affected by the overproduction of free radicals. Excess reactive
oxygen species (ROS) cannot be controlled by the antioxidant system and, thus, potentially
impact male fertility and hamper sperm quality parameters. Mitochondria are the driving
force of sperm motility; irregularities in their function may lead to apoptosis, alterations to …

[引用][C] Unraveling the harmful effect of oxidative stress on male fertility: A mechanistic insight. Front. Endocrinol. 2023; 14: 1070692

T Hussain, M Kandeel, E Metwally, G Murtaza… - 2023
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