Sphingolipids are important bioactive molecules that regulate basic aspects of cellular
metabolism and physiology, including cell growth, adhesion, migration, senescence,
apoptosis, endocytosis, and autophagy in yeast and higher eukaryotes. Since they have the
ability to modulate the activation of several proteins and signaling pathways, variations in
the relative levels of different sphingolipid species result in important changes in overall
cellular functions and fate. Sphingolipid metabolism and their route of synthesis are highly …