Untangling the ErbB signalling network
Y Yarden, MX Sliwkowski - Nature reviews Molecular cell biology, 2001 - nature.com
… bind the ErbB family of receptors, they trigger a rich network of signalling pathways,
culminating in responses ranging from cell division to death, motility to adhesion. The network is …
culminating in responses ranging from cell division to death, motility to adhesion. The network is …
[HTML][HTML] Disentangling ERBB signaling in breast cancer subtypes—A model-based analysis
S Kemmer, M Berdiel-Acer, E Reinz, J Sonntag… - Cancers, 2022 - mdpi.com
… the ERBB signaling network … the ERBB signaling network as displayed in Figure 2. Reaction
kinetics were modeled by the law of mass-action according to chemical reaction network …
kinetics were modeled by the law of mass-action according to chemical reaction network …
Ligand‐dependent responses of the ErbB signaling network: experimental and modeling analyses
MR Birtwistle, M Hatakeyama, N Yumoto… - Molecular systems …, 2007 - embopress.org
… Although it is clear that (i) different ErbB ligands can stimulate different network activation …
and cell fate, to understand how the ErbB signaling network controls cell fate, we must first …
and cell fate, to understand how the ErbB signaling network controls cell fate, we must first …
Integration of protein abundance and structure data reveals competition in the ErbB signaling network
… Using database mining, literature search, and manual curation, we assembled an ErbB
signaling network including the domains and linear motifs that mediate binary PPIs. A large …
signaling network including the domains and linear motifs that mediate binary PPIs. A large …
ErbB receptors: directing key signaling networks throughout life
T Holbro, NE Hynes - Annu. Rev. Pharmacol. Toxicol., 2004 - annualreviews.org
… A simplified scheme of ErbB signaling is illustrated in Figure 1. … The ErbB signaling
network. Ligands of the EGF family bind to their receptors causing the formation of different ErbB …
network. Ligands of the EGF family bind to their receptors causing the formation of different ErbB …
Signaling revealed by mapping molecular interactions: implications for ErbB-targeted cancer immunotherapies
… involved in the ErbB signaling network are elucidating these mechanisms, and promise to
facilitate the development of new ErbB-targeted … Untangling the ErbB signalling network …
facilitate the development of new ErbB-targeted … Untangling the ErbB signalling network …
[HTML][HTML] The ErbB signaling network and its potential role in endometrial cancer
G Androutsopoulos, I Styliara, E Zarogianni, N Lazurko… - Epigenomes, 2023 - mdpi.com
… Some of these pathways are part of the EGF system signaling network, which becomes …
Our aim is to provide an update on current knowledge of the signaling network of ErbB …
Our aim is to provide an update on current knowledge of the signaling network of ErbB …
[HTML][HTML] The logic of EGFR/ErbB signaling: theoretical properties and analysis of high-throughput data
R Samaga, J Saez-Rodriguez… - PLoS computational …, 2009 - journals.plos.org
… /ErbB signaling network For the reconstruction and qualitative analysis of the EGFR/ErbB
signaling network … Signaling networks are usually structured into input, intermediate and output …
signaling network … Signaling networks are usually structured into input, intermediate and output …
The ERBB network: at last, cancer therapy meets systems biology
Y Yarden, G Pines - Nature Reviews Cancer, 2012 - nature.com
… the ERBB (also known as HER) family (Fig. 1), and together they anchor a complex signalling
network that … and other mechanisms constitutively activate the network in a large variety of …
network that … and other mechanisms constitutively activate the network in a large variety of …
Therapeutically targeting ErbB3: A key node in ligand-induced activation of the ErbB receptor–PI3K axis
B Schoeberl, EA Pace, JB Fitzgerald, BD Harms… - … signaling, 2009 - science.org
… We believe that it represents the most detailed model of the ErbB signaling network to date
… of the ErbB signaling network, describing how stimulation of all four ErbB receptors with two …
… of the ErbB signaling network, describing how stimulation of all four ErbB receptors with two …
相关搜索
- receptor heterodimerization erbb signaling network
- protein abundance erbb signaling network
- endometrial cancer erbb signaling network
- erbb receptors key signaling networks
- cellular signaling networks
- systems biology erbb network
- signal transduction networks
- distinct signaling properties erbb 1
- erbb receptors quantitative protein interaction network
- erbb family network analysis
- development and cancer erbb signaling network
- signaling networks qualitative and semi-quantitative analysis
- cancer therapy erbb network
- erbb receptor signaling