Use of XyCAM RI for noninvasive visualization and analysis of retinal blood flow dynamics during clinical investigations

DC DeBuc, A Rege, WE Smiddy - Expert review of medical devices, 2021 - Taylor & Francis
DC DeBuc, A Rege, WE Smiddy
Expert review of medical devices, 2021Taylor & Francis
Introduction Ocular blood flow plays a critical role in eye health by nourishing the retinal and
ocular tissues with oxygen and nutrients and removal of ocular metabolic waste. Imaging of
retinal and optic blood flow may provide insights for early and more specific diagnoses of
ocular vascular disorder and facilitate eye-based biomarkers applicable to neurological
health assessment and research. Areas covered The ability of the XyCAM RI (Vasoptic
Medical Inc., MD, USA) to visualize and to analyze ocular blood flow dynamics XyCAM RI …
Introduction
Ocular blood flow plays a critical role in eye health by nourishing the retinal and ocular tissues with oxygen and nutrients and removal of ocular metabolic waste. Imaging of retinal and optic blood flow may provide insights for early and more specific diagnoses of ocular vascular disorder and facilitate eye-based biomarkers applicable to neurological health assessment and research.
Areas covered
The ability of the XyCAM RI (Vasoptic Medical Inc., MD, USA) to visualize and to analyze ocular blood flow dynamics XyCAM RI using laser speckle contrast imaging is reviewed and compared with concurrent clinical ophthalmic imaging technologies like optical coherence tomography – angiography (OCT-A), fundus imaging, fluorescein angiography (FA), indocyanine green angiography (ICGA), laser Doppler flowmetry (LDF), and laser speckle flowgraphy (LSFG).
Expert opinion
XyCAM RI, with its unprecedented imaging capabilities to assess blood flow dynamics provides a powerful tool to ophthalmic researchers and doctors to obtain greater clinical insights into the physiological status of the posterior segment and treatment approaches for various diseases in a very patient-friendly, noninvasive manner, unlike dye-based angiographic techniques such as FA or ICG. XyCAM RI is well suited as a modality that could close the gap between current screening and comprehensive eye exams.
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