Objective The aim of present study was to develop a simple, rapid, selective, sensitive and
robust reverse phase high performance liquid chromatographic method for quantification of
felodipine in rabbit plasma at the wavelength of 360 nm. Method Protein was precipitated
from rabbit plasma sample by addition of acetonitrile as a vehicle. An isocratic elution of
samples was performed on capcell pak C 8 DD S5 column (4.6 mm× 250 mm particle size 5
μm) column with mobile phase consisting 5 mM Phosphate Buffer (pH 4.8 adjusted with …