Background Volatile anesthetics have a dual effect on cell survival dependent on caveolin
expression. The effect of volatile anesthetics on cancer cell survival and death after
anesthetic exposure has not been well investigated. The authors examined the effects of
isoflurane exposure on apoptosis and its regulation by caveolin-1 (Cav-1). Methods The
authors exposed human colon cancer cell lines to isoflurane and proapoptotic stimuli and
assessed what role Cav-1 plays in cell protection. They evaluated apoptosis using assays …

CiNii 博士論文 - Volatile anesthetics protect cancer cells against tumor necrosis factor-related
apoptosis-inducing ligand-induced apoptosis via caveolins … Volatile anesthetics protect
cancer cells against tumor necrosis factor-related apoptosis-inducing ligand-induced
apoptosis via caveolins 揮発性麻酔薬はカベオリンを介してTumor Necrosis Factor-related
Apoptosis-inducing Ligand(TRAIL)誘発性アポトーシスから癌細胞を保護する … 揮発性麻酔薬
はカベオリンを介してTumor Necrosis Factor-related Apoptosis-inducing Ligand(TRAIL)誘発性 …