… Yet there is still much to be discovered even about the natural biology of this organism.
The pneumococcus is related to commensal members of the oral streptococci, it is primarily …

… pneumococcal disease is … pneumococcal pneumonia is 5.5 to 17.6 times higher in patients
with acquired immunodeficiency syndrome (AIDS), and in one study the rate of pneumococcal …

… There is no problem of greater importance than that relating to our … of pneumococcal
infection. From this brief and incomplete summary, it is evident that White's statement of 1938 [1] is …

… Complete attenuation of a virulent pneumococcus culture is secured only after several
passages in series, the first and second serum cultures generally being composed of a mixture of …

… pneumococci from phagocytosis by polymorphonuclear leukocytes. The virulence of
pneumococci is … Purified capsular polysaccharide elicits no inflammatory response when it is …

… disease in children in developing countries, even less is … what is and is not known about
the burden of pneumococcal … pneumococcal disease (IPD) rather than on pneumococcal …

… Elucidation of the molecular basis for capsule production among pneumococci is a field in
which we and other researchers are presently quite involved. The recent identification of short …

… Mere confinement to a phagocytic vacuole kills pneumococci … Capsular polysaccharide is
not the only pneumococcal surface … pneumococcal pneumonia is astounding. Our ignorance …

… However, it is likely that the pneumococcus is an example of a “fuzzy species,” and further
sampling of the fringes of the pneumococcal cluster may require us to update our definitions. …

… Obtaining appropriate antibiotic treatment for severe invasive pneumococcal infections is
now a major challenge in many regions of the world. The ground-breaking success of …