White matter alterations are associated with cognitive dysfunction decades after moderate-to-severe traumatic brain injury and/or posttraumatic stress disorder
Background Possible white matter (WM) alterations following moderate-to-severe traumatic
brain injury (TBI) and posttraumatic stress disorder (PTSD) and their relationship to clinical
outcome have yet to be investigated decades after trauma. We utilized structural magnetic
resonance imaging and diffusion tensor images to investigate brain volume and WM
alterations in Vietnam War veterans with moderate-to-severe TBI and/or PTSD examined 5
decades after trauma. Methods Data from 160 veterans—history of moderate-to-severe TBI …
brain injury (TBI) and posttraumatic stress disorder (PTSD) and their relationship to clinical
outcome have yet to be investigated decades after trauma. We utilized structural magnetic
resonance imaging and diffusion tensor images to investigate brain volume and WM
alterations in Vietnam War veterans with moderate-to-severe TBI and/or PTSD examined 5
decades after trauma. Methods Data from 160 veterans—history of moderate-to-severe TBI …
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