Withdrawal of fluticasone propionate from combined salmeterol/fluticasone treatment in patients with COPD causes immediate and sustained disease deterioration: a …
EFM Wouters, DS Postma, B Fokkens, WCJ Hop… - Thorax, 2005 - thorax.bmj.com
Background: Guidelines recommend inhaled corticosteroids (ICS) as maintenance treatment
for patients with chronic obstructive pulmonary disease (COPD) with a post-bronchodilator
forced expiratory volume in 1 second (FEV1)< 50% predicted and frequent exacerbations,
although they have only a small preventive effect on the accelerated decline in lung function.
Combined treatment with ICS and long acting β2 agonists (LABA) may provide benefit to the
stability of COPD, but it is unknown if withdrawal of ICS will result in disease deterioration …
for patients with chronic obstructive pulmonary disease (COPD) with a post-bronchodilator
forced expiratory volume in 1 second (FEV1)< 50% predicted and frequent exacerbations,
although they have only a small preventive effect on the accelerated decline in lung function.
Combined treatment with ICS and long acting β2 agonists (LABA) may provide benefit to the
stability of COPD, but it is unknown if withdrawal of ICS will result in disease deterioration …
[引用][C] Withdrawal of fluticasone propionate from combined salmeterol/fluticasone treatment in patients with COPD causes immediate and sustained disease …
EFM Wouters, DS Postma, B Fokkens, WCJ Hop… - … Medicine: COPD Update, 2005 - Elsevier
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