[HTML][HTML] Aberrant glycosylation and cancer biomarker discovery: a promising and thorny journey

M Wang, J Zhu, DM Lubman, C Gao - Clinical Chemistry and …, 2019 - degruyter.com
… on the pathophysiological implications of glycosylation. Fortunately, cutting-edge …
cancer-related glycosylation. Thus, glycans as well as aberrantly glycosylated protein-based cancer

[HTML][HTML] Hallmarks of glycosylation in cancer

J Munkley, DJ Elliott - Oncotarget, 2016 - ncbi.nlm.nih.gov
Aberrant glycosylation is often cited as a ‘hallmark of cancer’ … than aberrant glycosylation
being itself a hallmark of cancer, … that glycans play a role in every recognised cancer hallmark. …

[HTML][HTML] Aberrant glycosylation in cancer: a novel molecular mechanism controlling metastasis

A Magalhães, HO Duarte, CA Reis - Cancer cell, 2017 - cell.com
Glycosylation alterations are involved in several steps of human cancer pathogenesis. In this
issue of Cancer Cell, Agrawal et al. identified the glycosyltransferase FUT8 as a previously …

[HTML][HTML] Aberrant glycosylation associated with enzymes as cancer biomarkers

DL Meany, DW Chan - Clinical proteomics, 2011 - Springer
… of cancer biomarker discovery using aberrant glycosylation in three areas. First, changes in
glycosylation machinery such as glycosyltransferases/glycosidases could be used as cancer

Aberrant glycosylation as biomarker for cancer: focus on CD43

FM Tuccillo, A de Laurentiis, C Palmieri… - BioMed research …, 2014 - Wiley Online Library
cancer biomarkers. In particular, we will focus on the aberrant CD43 glycosylation as cancer
… to exploit the UN1 monoclonal antibody (UN1 mAb) to identify aberrant CD43 glycoforms. …

Aberrant protein glycosylation in cancer: implications in targeted therapy

JG Rodrigues, HO Duarte, CA Reis… - Biochemical Society …, 2021 - portlandpress.com
… Furthermore, such aberrant glycan structures play key roles in the acquisition of molecular
… anti-cancer targeted agents. In this review, we highlight the impact of glycosylation in cancer

[HTML][HTML] Epigenetic bases of aberrant glycosylation in cancer

F Dall'Olio, M Trinchera - International journal of molecular sciences, 2017 - mdpi.com
… in cancer. We see how different epigenetic mechanisms converge to regulate specific pathways
of cancer-… We also summarize the case of O-linked GlcNAc, in which glycosylation is not …

Altered glycosylation in cancer: A promising target for biomarkers and therapeutics

D Thomas, AK Rathinavel, P Radhakrishnan - … (BBA)-Reviews on Cancer, 2021 - Elsevier
cancerglycosylation machinery is associated with cancer progression and metastasis. We
also provide insights into the influence of aberrant glycosylation in the development of cancer

Glycosylation: a hallmark of cancer?

BN Vajaria, PS Patel - Glycoconjugate journal, 2017 - Springer
… remarkable progress in cancer research, … Aberrant glycosylation interferes with regulation
of cell adhesion, migration and proliferation. Glycosylation may represent a hallmark of cancer, …

Glycosylation in cancer: mechanisms and clinical implications

SS Pinho, CA Reis - Nature Reviews Cancer, 2015 - nature.com
… of cancer cells. The most-widely occurring changes in glycosylation associated with cancer
Aberrant glycosylation in cancer frequently involves an increase in sialyl Lewis x (SLe x ) …