… However, there is little evidence for the functional consequence of this aberrant glycosylation
during cancer progression. In human breast cancer cells, expression of sTn on MUC1 was …

… However, recent studies have shown that alterations in glycosylation can affect the conformational
arrangements of their extracellular domain, causing aberrant activation and signaling, …

… that aberrantly glycosylated, cancer-associated MUC1 is expressed in situ in most ovarian
cancers, but not in OSE and serous cystadenomas. Moreover, we show that the cancer-…

… Target proteins of O-glycosylation involved in metastasis Mucins are highly O-glycosylated
proteins and aberrant glycosylation of these structures has been implicated in cancer. In …

Background Changes in protein glycosylation are widely observed in tumor cells. N-glycan
branching through adding β1,6-linked N-acetylglucosamine (β1,6-GlcNAc) to an α1,6-linked …

… of the role of glycosylation in hematological malignancies. Here … of the relationship between
aberrant glycosylation and the … changes in glycosylation occur in the early stage of cancer …

… unbiased interrogation of cell surface glycosylation status. Here we … in glycosylation at the
surface of cancer cell and describe selected examples of receptors with aberrant glycosylation …

… found to be associated with cancer processes 69 , 70 . A growing body of evidence suggests
that aberrant glycosylation of proteins on the cancer cell surface or glycoproteins secreted …

… -V in human colon cancer cell WiDr. TIMP-1 was aberrantly glycosylated as characterized by
the … Compared with normal TIMP-1, the aberrantly glycosylated TIMP-1 showed the weaker …

… Cancer genetics is the basis of our understanding of the disease, and provides a context
to considering protein glycosylation as a modifier of cancer progression [41], [42]. Multiple …