… mechanisms converge to regulate specific pathways of cancer-… , in which glycosylation is
not only the target of epigenetic mechanisms, but contributes to the generation of the epigenetic …

… epigenetic regulation of glycogenes are about cancer. It is well-established that aberrant
glycosylation … that these changes are nonrandom: in cancer advancement, only the fittest cells …

… of epigenetic dysregulation of glyco-genes in cancer we … In these plots, the cut-off value for
significance was set at the base … to aberrant glycosylation profiles described in cancer and …

… as butyrate), have been widely used in cancer research, and it has been shown that their …
due to aberrant epigenetic changes in cancers (50). Cancer-associated aberrant epigenetic …

… Moreover, aberrant glycosylation is associated with disorders of the immune system, such as
… nephropathyCitation 43 and, for many years now, is well established in cancer.Citation 44 …

… However, the mechanistic basis remains poorly explored. … Moreover, epigenetic changes
in the glycosylation pattern make … of aberrant glycosylation in the development of cancer …

… (B) Genetic and epigenetic changes that inactivate AB blood group antigens. Aberrant
promoter hypermethylation in one copy of the gene (the first hit) is associated with either the loss …

… aberrant glycosylation being itself a hallmark of cancer, another perspective is that glycans
play a role in every recognised cancer … initiator of O-glycosylation) is frequently epigenetically …

… Aberrant glycosylation interferes with regulation of cell … the basis for inclusion of glycosylation,
as a new hallmark of … are deregulated at the level of epigenetics, transcription, post-…

… by highlighting aberrant glycosylation as an integral part of all recognized cancer hallmark
traits. … Although no specific links between hyper-O-GlcNAcylation and cancer cell epigenetic …