[HTML][HTML] Abiraterone acetate in the treatment of prostate cancer
… of patients suffering from prostate cancer. In this prevailing scenario, abiraterone acetate (AA)
has proved to be a boon for patients suffering from prostate cancer. AA selectively inhibits …
has proved to be a boon for patients suffering from prostate cancer. AA selectively inhibits …
Abiraterone and increased survival in metastatic prostate cancer
JS De Bono, CJ Logothetis, A Molina… - … England Journal of …, 2011 - Mass Medical Soc
… We hypothesized that inhibition of androgen biosynthesis with abiraterone acetate and
prednisone would improve overall survival among patients with advanced prostate cancer. …
prednisone would improve overall survival among patients with advanced prostate cancer. …
Selective inhibition of CYP17 with abiraterone acetate is highly active in the treatment of castration-resistant prostate cancer
G Attard, AHM Reid, R A'Hern, C Parker… - Journal of clinical …, 2009 - ascopubs.org
… , and irreversible inhibitor of CYP17, abiraterone, 13,14 which … the antitumor activity of
abiraterone acetate, this phase I … the antitumor activity of abiraterone acetate administered at 1,000 …
abiraterone acetate, this phase I … the antitumor activity of abiraterone acetate administered at 1,000 …
Abiraterone acetate for treatment of metastatic castration-resistant prostate cancer: final overall survival analysis of the COU-AA-301 randomised, double-blind …
K Fizazi, HI Scher, A Molina, CJ Logothetis… - The lancet …, 2012 - thelancet.com
… This final analysis confirms that abiraterone acetate significantly prolongs overall survival
in patients with metastatic castration-resistant prostate cancer who have progressed after …
in patients with metastatic castration-resistant prostate cancer who have progressed after …
[HTML][HTML] Abiraterone acetate and prednisolone with or without enzalutamide for high-risk non-metastatic prostate cancer: a meta-analysis of primary results from two …
… There was no evidence of a difference in metatasis-free survival when enzalutamide and
abiraterone acetate were administered concurrently compared with abiraterone acetate alone (…
abiraterone acetate were administered concurrently compared with abiraterone acetate alone (…
The role of abiraterone acetate in the management of prostate cancer: a critical analysis of the literature
G Sonpavde, G Attard, J Bellmunt, MD Mason… - European urology, 2011 - Elsevier
… Hence, the term castration-resistant prostate cancer (CRPC) is … analyse the emerging role of
abiraterone acetate (AA), a … The key enzyme inhibited by abiraterone acetate (AA) is CYP17, …
abiraterone acetate (AA), a … The key enzyme inhibited by abiraterone acetate (AA) is CYP17, …
Abiraterone in metastatic prostate cancer without previous chemotherapy
CJ Ryan, MR Smith, JS De Bono… - … England Journal of …, 2013 - Mass Medical Soc
… In this double-blind study, we randomly assigned 1088 patients to receive abiraterone acetate
(1000 mg) plus prednisone (5 mg twice daily) or placebo plus prednisone. The coprimary …
(1000 mg) plus prednisone (5 mg twice daily) or placebo plus prednisone. The coprimary …
Abiraterone acetate: a review of its use in patients with metastatic castration-resistant prostate cancer
SM Hoy - Drugs, 2013 - Springer
… Abiraterone acetate is approved … prostate cancer (CRPC). When administered in combination
with prednisone in a placebo-controlled, multinational phase III study, abiraterone acetate …
with prednisone in a placebo-controlled, multinational phase III study, abiraterone acetate …
Abiraterone for prostate cancer not previously treated with hormone therapy
ND James, JS de Bono, MR Spears… - … England Journal of …, 2017 - Mass Medical Soc
… Abiraterone acetate plus prednisolone improves survival in men with relapsed prostate
cancer. We assessed the effect of this combination in men starting long-term androgen-…
cancer. We assessed the effect of this combination in men starting long-term androgen-…
Abiraterone plus prednisone in metastatic, castration-sensitive prostate cancer
K Fizazi, NP Tran, L Fein, N Matsubara… - … England Journal of …, 2017 - Mass Medical Soc
… -resistant prostate cancer. We evaluated the clinical benefit of abiraterone acetate plus …
therapy in patients with newly diagnosed, metastatic, castration-sensitive prostate cancer. …
therapy in patients with newly diagnosed, metastatic, castration-sensitive prostate cancer. …
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