… Here, we focus our attention on ACE2, a primary receptor of SARS-CoV-2. We will discuss
… by SARS-CoV-2 for cell entry. Particular attention will be given to how the ACE2 soluble form …

… that the SARS-CoV-2 RBD–ACE2 and SARS-CoV RBD–ACE2 … , although some of the
ACE2 interactions observed both inside … of the SARS-CoV-2 and SARS-CoV RBD structures to …

… virus gains entrance into its host cell via the ACE2 receptor. How the known epidemiological
and clinical manifestation of SARS-CoV-… the ACE2 receptor due to receptor virus interaction …

… Angiotensin converting enzyme-2 (ACE2) receptors mediate the entry into the cell of three
strains of coronavirus: SARS-CoV, NL63 and SARS-CoV-2. ACE2 receptors are ubiquitous …

… cells that express ACE2 protein from … ACE2 is the receptor for SARS-CoV-2. Results in the
Cryo-EM experiments demonstrated that SARS-CoV-2 had a ten times higher affinity to ACE2 …

… glycoproteins (Env) with receptors [9], we propose a possible mechanism of the ACE2
function as a receptor for the SARS virus. The analysis of the ACE2 model could also help in the …

… involved in the SARS-CoV-2 S-protein interaction. Overall, we found human ACE2 receptor
… and the ACE2 PD showed even more reduced variation (Wilcoxon p-value = 0.0656, n = 65, …

… However, we and others have shown that WT ACE2 binds the SARS-CoV-2 spike RBD with
only modest affinity ( K D ∼ 15 nM) (15–17). ACE2 is therefore a good candidate for affinity …

… involved in the SARS-CoV-2 S-protein interaction. Overall, we found human ACE2 receptor
… index) value of 0.0168, and the ACE2 PD showed even more reduced variation (Wilcoxon p…

… In this review, we describe the genetic and molecular functions of the ACE2 receptor and
its relation with the physiological and pathological conditions to better understand how this …