… by the recruitment to the lungs and activation of immune and inflammatory cells. These
activated … Steroid receptors and co-activator proteins are known to stimulate gene expression by …

… the activation of the MAP kinase pathway. This leads to an increase in the transcription of
inflammatory mediators, causing lung inflammation. … factors and co-activator proteins is likely to …

… more susceptible to lung inflammation. Knowledge of the … lung inflammation and injury. This
review describes the redox control and involvement of nuclear factor-kB and activator protein…

… , ROS has been implicated in initiating inflammatory responses in the lungs through the
activation of transcription factors, such as nuclear factor (NF)-κB and activator protein (AP)-1, and …

… suggesting that PPARα and PPARγ activators may be helpful in the treatment of lung … T
cells (NF-AT), CAAT/enhancer-binding protein (C/EBP) and activator protein 1 (AP-1) [70,91,…

… control the extent of lung inflammation by modulating the activation of NF-κB. … lung inflammation
is self-regulated and that endogenous mediators control the extent of lung inflammatory …

… of plasminogen activator inhibitor-1 (… activator is an important mediator of lung inflammation
and remodeling. However, further preclinical characterization of uPA as a drug target for lung …

… /antioxidant imbalance in the lungs of asthmatics may lead to activation of redox-sensitive …
of macrophage inflammatory protein 1α and macrophage inflammatory protein 1β that are …

… fibrotic lung disease. This article reviews our current understanding of the mechanisms leading
to the activation of the coagulation cascade in response to lung … by activating protein C. …

… Chronic inflammatory lung diseases are characterized by increased expression of multiple
inflammatory genes following activation by proinflammatory transcription factors, such as …