[HTML][HTML] Methylome-wide sequencing detects DNA hypermethylation distinguishing indolent from aggressive prostate cancer

JM Bhasin, BH Lee, L Matkin, MG Taylor, B Hu, Y Xu… - Cell reports, 2015 - cell.com
… molecular mechanisms behind aggressive prostate cancer by comparing DNA methylation
profiles between benign prostate, indolent prostate cancer, and aggressive prostate cancer. …

The DNA methylation landscape of advanced prostate cancer

SG Zhao, WS Chen, H Li, A Foye, M Zhang… - Nature …, 2020 - nature.com
DNA methylation patterns between primary prostate cancer (PCa) and benign prostate tissue,
… Metastatic castration-resistant prostate cancer (mCRPC) is the lethal form of the disease. …

DNA methylation in prostate cancer

LC Li, ST Okino, R Dahiya - … et Biophysica Acta (BBA)-Reviews on Cancer, 2004 - Elsevier
… in cell cycle control, signal transduction and hormonal response provides a further growth
advantage, leading to locally advanced prostate cancer. Further function loss of genes in …

DNA methylation changes in prostate cancer

W Goering, M Kloth, WA Schulz - Cancer Epigenetics: Methods and …, 2012 - Springer
… of prostate cancer, the most prevalent malignant tumor in … research on DNA methylation
alterations in this cancer type. … between indolent and aggressive prostate cancers at the time …

Development of castration resistant prostate cancer can be predicted by a DNA hypermethylation profile

JC Angulo, G Andrés, N Ashour… - The Journal of …, 2016 - Elsevier
… the ZNF gene family by DNA hypermethylation. Down-regulation of ZNF132 due to epigenetic
silencing is associated with aggressive PCa 27 but to our knowledge hypermethylation of …

[HTML][HTML] Intratumor DNA methylation heterogeneity reflects clonal evolution in aggressive prostate cancer

D Brocks, Y Assenov, S Minner, O Bogatyrova… - Cell reports, 2014 - cell.com
tumor sites, premalignant lesions, and lymph node metastases within five cases of prostate
cancer, we demonstrate that both DNA methylation … Furthermore, we show cases of genetic or …

Effect of DNA methylation on identification of aggressive prostate cancer

JJ Alumkal, Z Zhang, EB Humphreys, C Bennett… - Urology, 2008 - Elsevier
… silencing in many cancers. In this study, we assessed the effect of DNA methylation on
the identification of recurrent prostate cancer. …

[HTML][HTML] The emerging roles of DNA methylation in the clinical management of prostate cancer

AS Perry, R Foley, K Woodson… - … -related cancer, 2006 - erc.bioscientifica.com
cancer cells for more than 20 years. The role of DNA methylation in malignant transformation
of the prostate … of tumour development to the advanced stages of androgen independence. …

A DNA hypermethylation profile reveals new potential biomarkers for prostate cancer diagnosis and prognosis

N Ashour, JC Angulo, G Andrés, R Alelú… - … Prostate, 2014 - Wiley Online Library
… the specific gene hypermethylation profile for prostate cancer … discriminate patients with
indolent and aggressive tumors. … whether a prostate cancer gene hypermethylation profile could …

epiCaPture: a urine DNA methylation test for early detection of aggressive prostate cancer

E O'Reilly, AV Tuzova, AL Walsh, NM Russell… - JCO precision …, 2019 - ascopubs.org
… Herein, we present the results of one of two DNA methylationTumor Markers) guidelines
on correct reporting of prognostic biomarker research. The Epigenetic Cancer of the Prostate