… suppression responses, such as cellular senescence. These new findings demonstrate how
cancer, senescence, and aging can be linked in part through common metabolic processes. …

… pathway, enabling them to escape malignancy. The senescent cell became a major actor of
the aging process, among others, by the acquisition of the senescence-associated secretory …

… senescence, including the signals that trigger senescence, the molecular pathways by which
cells enter senescence, and evidence that supports its role in tumorigenesis and aging. J. …

… ability of inducing cell senescence through novel mechanisms that underpin aging processes.
… models have advanced our understanding of pathways that lead to age-related features, …

… Once cells have entered senescence, they cease to divide and … Cellular senescence is
thought to play an important role in tumor suppression and to contribute to organismal aging, but …

… There may be other, as yet poorly characterized p53- and pRB-independent pathways that
can establish or maintain the senescence growth arrest, but the p53/p21 and p16 INK4a /pRB …

… conservation of aging phenotypes from bacteria to humans, aging pathways might have
been … older cells, aging pathways, and particularly those associated with cellular senescence …

… aging kidney. Here we discuss new progress in understanding renal aging, focusing on
mechanisms of cell senescence … , all pathways associated with alleviating cell senescence in the …

… cell senescence genes in a pathway context, we extracted PPIs between 504 cell senescence
… This provides a broader biological picture associated with cell aging. To this end, a non-…

… aging through multiple pathways. In this review, we summarized the main mechanisms of
cellular senescence, mitochondrial malfunction and aging … involved in the aging process may …