Altered glycosylation in tumours focused to cancer diagnosis

R Peracaula, S Barrabés, A Sarrats, PM Rudd… - Disease …, 2008 - content.iospress.com
The lack of specific and sensitive tumour markers for early detection of cancer is driving a
search for new approaches that could identify biomarkers. Markers are needed to alert …

Altered glycosylation in cancer: A promising target for biomarkers and therapeutics

D Thomas, AK Rathinavel, P Radhakrishnan - … (BBA)-Reviews on Cancer, 2021 - Elsevier
… how altered glycosylation machinery is associated with cancer … of aberrant glycosylation
in the development of cancer … a diagnostic tool to discriminate endometriosis from ovarian …

Clinical aspects of altered glycosylation of glycoproteins in cancer

TF Orntoft, EM Vestergaard - … : An International Journal, 1999 - Wiley Online Library
Alteration of the expression of carbohydrate structures is frequently observed in tumor cells.
This review summarizes the different changes of O‐ and N‐linked glycoproteins observed in …

Altered glycosylation in prostate cancer

RR Drake, EE Jones, TW Powers… - Advances in cancer …, 2015 - Elsevier
… of the prostate gland is annually the most common newly diagnosed cancer in men, and
second most fatal cancer in men in the United States. It is estimated that in 2013, there would be …

Glycosylation markers in cancer

A Silsirivanit - Advances in clinical chemistry, 2019 - Elsevier
… are often used as markers for diagnosis, monitoring treatment and prognosis. … cancer would
likely facilitate diagnosis and treatment. In this chapter, the alteration of protein glycosylation

Alterations in glycosylation as biomarkers for cancer detection

CA Reis, H Osorio, L Silva, C Gomes… - Journal of clinical …, 2010 - jcp.bmj.com
… of altered glycosylation in cancer initiation, and despite information on the mechanisms that
generate abnormal glycosylation … collected 5 years before diagnosis of ovarian cancer.125 …

Evidence of altered glycosylation of serum proteins prior to pancreatic cancer diagnosis

S Krishnan, HJ Whitwell, J Cuenco… - International journal of …, 2017 - mdpi.com
… -9) in early detection of cancer. In conclusion, we provide preliminary evidence of altered
glycosylation of several serum proteins prior to pancreatic cancer diagnosis, warranting further …

Altered glycosylation of proteins produced by malignant cells, and application for the diagnosis and immunotherapy of tumours

A Kobata, J Amano - Immunology and cell biology, 2005 - Wiley Online Library
… In this review, current knowledge of the altered N-glycosylation of glycoproteins produced
in tumour cells will be summarized to help readers to consider the importance of this topic. …

Altered tumor-cell glycosylation promotes metastasis

I Häuselmann, L Borsig - Frontiers in oncology, 2014 - frontiersin.org
… microenvironment and thereby promote cancer progression. The identification of mechanisms
how tumor glycans contribute to metastasis may help to improve diagnosis, prognosis, …

Aberrant glycosylation associated with enzymes as cancer biomarkers

DL Meany, DW Chan - Clinical proteomics, 2011 - Springer
… utilities in the personalized approach to cancer diagnosis and treatment: Her-2/… altered
glycosylation patterns allow the distinction of PSA from seminal fluid (normal) and prostate cancer