… not responded adequately to conventional therapy. Combination therapy with methotrexate
(… Whether anti-TNF therapy protects joints from structural damage is under investigation. One …

… Studies suggest that other chronic inflammatory diseases will benefit from anti-cytokine
therapies. However, there is a growing body of clinical evidence that neutralization of TNF-α is …

… new immune system modulators as therapeutic tools. Other immunosuppressive agents …
medical therapies available for certain subgroups of patients. Furthermore, biological therapies …

… Therefore, specific anti-cytokine therapies may be effective in … one cytokine to obtain
significant therapeutic benefits in an … and their potential as therapeutic targets. Although we …

… the same therapeutic tools is problematic. Instead, current biologic therapies target certain
… Although anticytokine therapy of common autoimmune diseases, such as RA or IBD, has …

… (Abs) has prompted a therapeutic approach that aims to supply … Novel anti-cytokine therapeutic
compounds, based on … long-term use of anti-cytokine immunotherapy using allogenic or …

… The remarkable anti-inflammatory activity of a first neutralizing monoclonal anti-TNF antibody
in RA patients revealed the potential of anti-cytokine therapy [12] and has subsequently …

… , and identify key targets for anti-cytokine treatments. We then present … anti-cytokine
therapeutic approaches. We further discuss progresses in the promising field of active anti-cytokine …

This is a review looking at anti cytokine therapy in Rheumatoid Arthritis (RA), Psoriatic
Arthritis (PSA) and Ankylosing Spondylitis (AS). The review explores the similarities and …

… of anti-cytokine therapy in asthma, or due perhaps to biological redundancy when targeting
single cytokines, anti-cytokine therapy … the value of biological therapy in severe asthma; the …