Marine-derived indole alkaloids and their biological and pharmacological activities

JT Wibowo, P Ahmadi, SI Rahmawati, A Bayu… - Marine Drugs, 2021 - mdpi.com
… , anticancer, antidiabetic, and antiparasitic activities. This review reports the indole alkaloids
… The marine-derived indole alkaloids reported from 2016 to 2021 were collected from …

Current scenario of indole derivatives with potential anti-drug-resistant cancer activity

Y Jia, X Wen, Y Gong, X Wang - European Journal of Medicinal Chemistry, 2020 - Elsevier
indole derivatives including indole alkaloids, hybrids, dimers and metal complexes with
potential … are fruitful matrices for the discovery of novel anticancer agents to tackle drug-resistant …

Recent development in indole derivatives as anticancer agents for breast cancer

K Kaur, V Jaitak - … Current Medicinal Chemistry-Anti-Cancer …, 2019 - ingentaconnect.com
… of indole-based heterocyclic compounds as anticanceranticancer potential through induction
of apoptosis, antimetastatic and inhibition of antiapoptotic Bcl-2 protein. Rotation of indole

Synthesis of novel analogues of marine indole alkaloids: Mono (indolyl)-4-trifluoromethylpyridines and bis (indolyl)-4-trifluoromethylpyridines as potential anticancer …

WN Xiong, CG Yang, B Jiang - Bioorganic & medicinal chemistry, 2001 - Elsevier
… potent and selective antitumor agents. As a part of our ongoing structure–activity relationship
study on indole alkaloids, we incorporated fluorines into indole alkaloids to investigate the …

Isolation, solid-state structure determination, in silico and in vitro anticancer evaluation of an indole amino acid Alkaloid L-Abrine

S Laskar, O Espino… - Current Cancer Drug …, 2019 - ingentaconnect.com
… and the solid-state structure of this indolealkaloid was determined by X-ray crystallographic
… Sulforhodamine B (SRB) colorimetric assay was used for in vitro anticancer evaluation …

Indole alkaloid marine natural products: An established source of cancer drug leads with considerable promise for the control of parasitic, neurological and other …

W Gul, MT Hamann - Life sciences, 2005 - Elsevier
… products have largely been explored as anticancer agents. The … on indole alkaloids of marine
origin and also highlights our own research. Specific biological activities of indole alkaloids

Antifungal indole alkaloids from Winchia calophylla

ML Yang, J Chen, M Sun, DB Zhang, K Gao - Planta Medica, 2016 - thieme-connect.com
… The medical applications of indole alkaloids as a source of anticancer drugs have been of
great interest to the fields of natural products, medicinal chemistry, and pharmacology [27], [28]…

Indole derivatives as anticancer agents for breast cancer therapy: a review

J Singh Sidhu, R Singla, V Jaitak - Anti-Cancer Agents in …, 2016 - ingentaconnect.com
… Evodiamine, (36) a natural indole alkaloid obtained from Chinese herb Evodiarutaecarp
induces … It also enhances the anticancer potential of doxorubicin on cancerous cells showing …

Cytotoxic Indole Alkaloid 3α-Acetonyltabersonine Induces Glioblastoma Apoptosis via Inhibition of DNA Damage Repair

Y Li, Y Zhao, X Zhou, W Ni, Z Dai, D Yang, J Hao, L Luo… - Toxins, 2017 - mdpi.com
… are well known for their antitumor bioactivities. Natural products … indole alkaloids has been
the spotlight of antitumor drug … antitumor products from medicinal plants, indole alkaloids were …

Indole molecules as inhibitors of tubulin polymerization: potential new anticancer agents

SA Patil, R Patil, DD Miller - Future medicinal chemistry, 2012 - Taylor & Francis
… a broad anti-tumor spectrum and they represent one of the most significant classes of
anticancer agents. In the past few years, several small synthetic molecules that have an indole