… The topsentins fit nicely into this scheme and reinforce the idea that the complex indole
alkaloid … to discover new antitumor drugs using natural marine bis(indole) alkaloids as leading …

… , antibacterial and antitumor activity, as well as to methods for their production including
biosynthesis from cultures. Similarly, patents regarding the anticancer potential of welwistatin, …

… indole alkaloids. Both α- and β-carboline derivatives have been shown to display potent
anticancer … of several naturally occurring isoquinoline and indole alkaloids, some of them being …

… new effective anticancer indole alkaloids from … alkaloid fraction of the methanol extract of
Tabernaemontana elegans yielded three novel (4-6) and five known (7-11) bisindole alkaloids …

… In summary, these results imply that affinisine may be a potential anticancer agent. However,
there is a need for further studies with the compound, in addition to testing the molecule in …

… indole alkaloids with enhanced multidrug resistance (MDR) reversing activity in cancer, two
major epimeric alkaloids … (2), were derivatized by alkylation of the indole nitrogen. Twenty-six …

… anticancer, anti-inflammatory, antimalarial etc. In this review, we have discussed various …
This enzyme can be inhibited by Apicidin which is an indole alkaloid [5]. Malaria along with …

… Prenylated indole alkaloids, which are mainly produced by … eight structurally diverse
prenylated indole alkaloids, including an … ATB may be a promising anti-tumor lead compound. …

… a large number of potential anticancer leads [32].Alkaloids that have been developed into
highly … studied plants, produces nearly 130 terpenoid indole alkaloids [35] used in combination …

A new series of indole analogues based on our earlier lead compound, 2-(1H-indol-5-yl)-4-(3,4,5-trimethoxyphenyl)-1H-imidazo[4,5-c]pyridine
(42), was prepared as tubulin inhibitors in …