… to the antioxidant response element (ARE) recently identified in the upstream region of
the rat … revealed the presence the potential binding site the AP1 andrelatedprotein(s)contained …

… : Role of APl binding site contained within human antioxidant response element. J Biol Chem
… -1, a nuclear protein that facilitates AP-1 DNA binding activity. EMBG J 11: 653-665, 1992. …

… ) site. The AP-1 site is an element that is transcriptionally activated by tetradecanoyl-phorbol-…
The HRE, being a composite ARE, can serve as a binding site for the different bZIP proteins. …

… also contains several Sp-l binding sites, a consensus AP1 site and several AP-1-like … an
antioxidant response element similar to those recently detected in the promoter region of several …

… that a putative Ets factor binding site (36) at this … -κB binding sequence was not competitive
for any of the three specific bands (lane 8). Competitors containing consensus AP-1 binding …

… family members in the regulation of ARE-containing genes, we were interested in further
evaluating the functional significance of the internal AP-1-binding site within ARE4. Because …

… subunit genes were in fact responsive to heme but not … antioxidant response element were
activated by this agent. The heme response element resembles the consensus binding sites …

… AP1-like and AP1/NFE2 sites (Figure 3). We next asked whether both AP1-like and AP1/NFE2
sites … using nuclear extracts isolation kit (Active Motif). Both fractions were subjected to 10…

… Our results indicate that AP-1 binding sites (TREs) represent antioxidant response elements
(AREs). This idea is supported by recent studies analyzing the transcriptional control of …

… element (ARE) found in the 5‘-flanking region of the rat glutathione S-… responsive to
TPA and shows some sequence similarity to an AP-1-binding site (Jun/Fos recognition motif…