… β-Lactam resistance rates have been observed to be lower in … of β-lactamases specifically
from the Asia-Pacific region or … bacilli isolated from patients in many Asia-Pacific countries (8…

… β-lactamase-producing Enterobacteriaceae in children and young adults in the South-…
Asia and the Western Pacific. We also mapped the prevalence of extended-spectrum β-lactamase-…

… bacterium from attack by naturally occurring β-lactams. Their ancestors were presumably …
homology with β-lactamases possessing an active-site serine. Metallo-β-lactamases also exist, …

… Susceptibilities to eight antimicrobial agents of extended-spectrum β-lactamase-producing
(ESBL+) and –non-producing (ESBL-) E. coli (A) and K. pneumoniae (B) isolates from …

… North America reported the lowest rates of extended-spectrum β-lactamase (ESBL)-producing
Klebsiella pneumoniae and Escherichia coli both overall (12.8% and 4.7%, respectively) …

… that produce extended-spectrum β-lactamases (ESBLs) are … to include uropathogens
collected from Asia-Pacific countries. The first … Therefore, in this Asia-Pacific multicentre survey, …

… agents whereby a β-lactam is formulated with a β-lactamase inhibitor to extend the … the
β-lactam antibiotic despite the effect of hydrolysing β-lactamase enzymes, although β-lactamase …

… ) from 32 centres in 11 countries in the Asia–Pacific region and tested their in vitro susceptibility
to … High rates of extended-spectrum β-lactamase (ESBL)-producing E. coli and Klebsiella …

… pathogens in the Asia Pacific area was … Asia-Pacific region [2, 3]. In 2009, SMART was
expanded to include surveillance of Gram-negative pathogens causing UTIs in the Asia-Pacific …

… The activity of tigecycline is also unaffected by other mechanisms such as β-lactamase
production, penicillin-binding protein alterations, macrolide efflux pumps and DNA gyrase …