… Extended-spectrum β-lactamase (ESBL)-producers typically had a more resistant profile …
Enterobacteriaceae recovered from patients in Asia–Pacific with intra-abdominal infections. …

… Original-spectrum β-lactamases (TEM-type β-lactamases without substitutions at amino
acid positions 104, 164 or 238, or SHV-type β-lactamases without substitutions at amino acid …

… β-lactamases have evolved in bacteria: the serine-β-lactamases and the metallo-β-lactamases…
affect the activity of serine-β-lactamases, but do inhibit metallo-β-lactamases—a largely …

… , these antimicrobial agents may be hydrolysed by Ambler class B metallo-β-lactamases (MBLs)
as well as by carbapenem-hydrolysing class D β-lactamases (class D carbapenemase). …

… -OXA-48 Ambler class D β-lactamases [9]. The two novel β-lactam combination agents only
… Hence, the novel β-lactam combination agents tested in the present study seem to be less …

… Metallo-β-lactamases (MBLs) hydrolyze all classes of β-lactams except monobactams and
are not inhibited by classic serine β-lactamase inhibitors. Gram-negative pathogens isolated …

… Asia, Europe, and Latin America to non–b-lactam antimicrobial classes. Clinical isolates
harboring metallo-b-lactamases … b-lactamase enzymes producing resistance to b-lactam agents, …

… β-lactams penicillin, cephalosporins, monobactams and carbapenems have a β-lactam ring
which can be hydrolysed by βlactamases … a multitude of β-lactams has led to overproduction …

… AmpC β-lactamase genes, typically blaCMY-2 and blaDHA-1. A global surveillance study
showed that, in Southeast and East Asia, the nosocomial detection rates of AmpC β-lactamase …

… resistance gene predictions for selected beta-lactamase genes, and the strains included from
… responsible for the higher beta-lactam resistance associated with ST131 in Southeast Asia …