Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes

…, Genetic Investigation of ANthropometric Traits (GIANT) … - … genetics, 2012 - nature.com
… To extend understanding of the genetic architecture and molecular basis of type 2 diabetes
(T2D), we conducted a meta-analysis of genetic variants on the Metabochip, including …

Determination of the genetic architecture of seed size and shape via linkage and association analysis in soybean (Glycine max L. Merr.)

Z Hu, H Zhang, G Kan, D Ma, D Zhang, G Shi, D Hong… - Genetica, 2013 - Springer
… In this study, we performed a genetic analysis to determine the genetic architecture of
soybean seed size and shape via linkage and association analyses. We used 184 recombinant …

Genome-wide association analysis of psoriatic arthritis and cutaneous psoriasis reveals differences in their genetic architecture

PE Stuart, RP Nair, LC Tsoi, T Tejasvi, S Das… - … of Human Genetics, 2015 - cell.com
… To discern differences in genetic risk factors for PsA and cutaneous-only … association study
(GWAS) of 1,430 PsA case subjects and 1,417 unaffected control subjects. Meta-analysis of …

Genome-wide association analysis reveals insights into the genetic architecture of right ventricular structure and function

N Aung, JD Vargas, C Yang, K Fung, MM Sanghvi… - … genetics, 2022 - nature.com
… in our understanding of the genetic architecture of RV phenotypes in the general population
and provide a foundation to characterize the genetic drivers of RV remodeling in the future. …

Integrating image-based phenomics and association analysis to dissect the genetic architecture of temporal salinity responses in rice

MT Campbell, AC Knecht, B Berger, CJ Brien… - Plant …, 2015 - academic.oup.com
… To assess the genetic basis of plant growth … association mapping. Coupled with temporal
fluorescence imaging, we present, to our knowledge, new insights into the genetic architecture

Exploring the genetic architecture of root-related traits in mediterranean bread wheat landraces by genome-wide association analysis

R Rufo, S Salvi, C Royo, JM Soriano - Agronomy, 2020 - mdpi.com
Background: Roots are essential for drought adaptation because of their involvement in water
and nutrient uptake. As the study of the root system architecture (RSA) is costly and time-…

The genetic architecture of appendicular lean mass characterized by association analysis in the UK Biobank study

YF Pei, YZ Liu, XL Yang, H Zhang, GJ Feng… - Communications …, 2020 - nature.com
… wide association study (GWAS) with 450,243 UK Biobank participants to uncover its genetic
architecture… Our findings revealed a large number of genetic variants for lean body mass and …

Genetic Architecture of Aluminum Tolerance in Rice (Oryza sativa) Determined through Genome-Wide Association Analysis and QTL Mapping

AN Famoso, K Zhao, RT Clark, CW Tung… - … genetics, 2011 - journals.plos.org
… a smaller target region following GWA analysis. In this study, the genetic architecture of rice
Al tolerance was investigated via bi-parental QTL analysis in two mapping populations using …

[HTML][HTML] Joint association analysis method to dissect complex genetic architecture of multiple genetically related traits

F Lin, G Qi, T Xu, X Lou, Y Hong, H Xu - The Crop Journal, 2020 - Elsevier
… an analysis that jointly considers the gene-gene and gene -environment interactions. … a
joint association analysis method for mapping common or phenotype-specific genetic causal …

[HTML][HTML] Genome-wide association analysis reveals new insights into the genetic architecture of defensive, agro-morphological and quality-related traits in cassava

IY Rabbi, SI Kayondo, G Bauchet, M Yusuf… - Plant Molecular …, 2022 - Springer
… Our interest in this study was to identify the genetic architecture of selected traits rather than
location- or year-specific QTLs. We collapsed plot observations for each genotype to a single …