Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes
…, Genetic Investigation of ANthropometric Traits (GIANT) … - … genetics, 2012 - nature.com
… To extend understanding of the genetic architecture and molecular basis of type 2 diabetes
(T2D), we conducted a meta-analysis of genetic variants on the Metabochip, including …
(T2D), we conducted a meta-analysis of genetic variants on the Metabochip, including …
Determination of the genetic architecture of seed size and shape via linkage and association analysis in soybean (Glycine max L. Merr.)
… In this study, we performed a genetic analysis to determine the genetic architecture of
soybean seed size and shape via linkage and association analyses. We used 184 recombinant …
soybean seed size and shape via linkage and association analyses. We used 184 recombinant …
Genome-wide association analysis of psoriatic arthritis and cutaneous psoriasis reveals differences in their genetic architecture
… To discern differences in genetic risk factors for PsA and cutaneous-only … association study
(GWAS) of 1,430 PsA case subjects and 1,417 unaffected control subjects. Meta-analysis of …
(GWAS) of 1,430 PsA case subjects and 1,417 unaffected control subjects. Meta-analysis of …
Genome-wide association analysis reveals insights into the genetic architecture of right ventricular structure and function
… in our understanding of the genetic architecture of RV phenotypes in the general population
and provide a foundation to characterize the genetic drivers of RV remodeling in the future. …
and provide a foundation to characterize the genetic drivers of RV remodeling in the future. …
Integrating image-based phenomics and association analysis to dissect the genetic architecture of temporal salinity responses in rice
… To assess the genetic basis of plant growth … association mapping. Coupled with temporal
fluorescence imaging, we present, to our knowledge, new insights into the genetic architecture …
fluorescence imaging, we present, to our knowledge, new insights into the genetic architecture …
Exploring the genetic architecture of root-related traits in mediterranean bread wheat landraces by genome-wide association analysis
R Rufo, S Salvi, C Royo, JM Soriano - Agronomy, 2020 - mdpi.com
Background: Roots are essential for drought adaptation because of their involvement in water
and nutrient uptake. As the study of the root system architecture (RSA) is costly and time-…
and nutrient uptake. As the study of the root system architecture (RSA) is costly and time-…
The genetic architecture of appendicular lean mass characterized by association analysis in the UK Biobank study
… wide association study (GWAS) with 450,243 UK Biobank participants to uncover its genetic
architecture… Our findings revealed a large number of genetic variants for lean body mass and …
architecture… Our findings revealed a large number of genetic variants for lean body mass and …
Genetic Architecture of Aluminum Tolerance in Rice (Oryza sativa) Determined through Genome-Wide Association Analysis and QTL Mapping
… a smaller target region following GWA analysis. In this study, the genetic architecture of rice
Al tolerance was investigated via bi-parental QTL analysis in two mapping populations using …
Al tolerance was investigated via bi-parental QTL analysis in two mapping populations using …
[HTML][HTML] Joint association analysis method to dissect complex genetic architecture of multiple genetically related traits
… an analysis that jointly considers the gene-gene and gene -environment interactions. … a
joint association analysis method for mapping common or phenotype-specific genetic causal …
joint association analysis method for mapping common or phenotype-specific genetic causal …
[HTML][HTML] Genome-wide association analysis reveals new insights into the genetic architecture of defensive, agro-morphological and quality-related traits in cassava
… Our interest in this study was to identify the genetic architecture of selected traits rather than
location- or year-specific QTLs. We collapsed plot observations for each genotype to a single …
location- or year-specific QTLs. We collapsed plot observations for each genotype to a single …
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