Benzo (a) pyrene decreases brain and ovarian aromatase mRNA expression in Fundulus heteroclitus
… expression of the P450 enzyme aromatase genes could be a target for reproductive or
developmental dysfunction caused by BaP exposure. Aromatase … are two isoforms of aromatase, a …
developmental dysfunction caused by BaP exposure. Aromatase … are two isoforms of aromatase, a …
Effects of benzo (a) pyrene exposure on killifish (Fundulus heteroclitus) aromatase activities and mRNA
… mRNA levels, our results showed a seasonal difference in the BaP effects on killifish female
brain aromatase activity. Following the winter BaP exposure female brain aromatase activity …
brain aromatase activity. Following the winter BaP exposure female brain aromatase activity …
Altered gene expression: A mechanism for reproductive toxicity in zebrafish exposed to benzo [a] pyrene
JL Hoffmann, JT Oris - Aquatic Toxicology, 2006 - Elsevier
… The objectives of this study were to: (1) determine the effect of exposure to waterborne
benzo[a]pyrene (B[a]P) (0, 1.5 and 3.0μg/L) for 56 days on egg production and OSI in female …
benzo[a]pyrene (B[a]P) (0, 1.5 and 3.0μg/L) for 56 days on egg production and OSI in female …
… and PPAR-mediated aromatase downregulation in female Sprague–Dawley rats following combined oral exposure to benzo [a] pyrene and di-(2-ethylhexyl) …
C Xu, JA Chen, Z Qiu, Q Zhao, J Luo, L Yang, H Zeng… - Toxicology letters, 2010 - Elsevier
… mRNA levels compared to controls (P < 0.05). Additionally, significant differences of P450Arom
mRNA expression … PPAR-α and PPAR-γ mRNA expression and reached the statistically …
mRNA expression … PPAR-α and PPAR-γ mRNA expression and reached the statistically …
The cigarette smoke constituent benzo [a] pyrene disrupts metabolic enzyme, and apoptosis pathway member gene expression in ovarian follicles
JC Sadeu, WG Foster - Reproductive toxicology, 2013 - Elsevier
… Therefore, the objective of this study was to quantify mRNA expression … mRNA expressions
were lower compared to expression on day 12. While aromatase mRNA expression …
were lower compared to expression on day 12. While aromatase mRNA expression …
Embryonic exposure to benzo (a) pyrene inhibits reproductive capability in adult female zebrafish and correlation with DNA methylation
D Gao, J Lin, K Ou, Y Chen, H Li, Q Dai, Z Yu… - Environmental …, 2018 - Elsevier
… the effects of embryonic short-term exposure to benzo(a)pyrene (BaP), a model … mRNA
levels of follicle-stimulating hormone, luteinizing hormone, ovarian cytochrome P450 aromatase …
levels of follicle-stimulating hormone, luteinizing hormone, ovarian cytochrome P450 aromatase …
CYP1C1 Messenger RNA Expression is Inducible by Benzo[a]pyrene in Fundulus heteroclitus Embryos and Adults
… CYP1C1 mRNA expression was constitutively higher than CYP1A in brain, spleen, eye,
and gonad, while CYP1A was higher in gastrointestinal tract (GI), heart, gill, and liver. Kidney …
and gonad, while CYP1A was higher in gastrointestinal tract (GI), heart, gill, and liver. Kidney …
Mechanism of benzo (a) pyrene induction of alpha-human chorionic gonadotropin gene expression in human lung tumor cells.
DT Wong, DK Biswas - The Journal of cell biology, 1985 - rupress.org
… Ectopic hormone and inappropriate gene expression are commonly found to be associated
with neoplastic transformation of cells. BaP and several other members of the PAHs have …
with neoplastic transformation of cells. BaP and several other members of the PAHs have …
Benzo[a]pyrene Effects on Reproductive Endpoints in Fundulus heteroclitus
F Booc, C Thornton, A Lister, D MacLatchy… - Toxicological …, 2014 - academic.oup.com
… aromatase mRNA expression found in both F. heteroclitus larvae and adults (Dong et al.,
2008) and ovarian aromatase … the reduction in aromatase expression would hypothetically lead …
2008) and ovarian aromatase … the reduction in aromatase expression would hypothetically lead …
Mechanistic evaluation of benzo [a] pyrene's developmental toxicities mediated by reduced Cyp19a1b activity
KM Alharthy, FF Albaqami, C Thornton… - Toxicological …, 2017 - academic.oup.com
… The focus of this study was on brain aromatase expressed by … ’s ability to disrupt aromatase
gene expression and activity, … no significant effect on cyp19a1b expression in either BaP-…
gene expression and activity, … no significant effect on cyp19a1b expression in either BaP-…
相关搜索
- aromatase gene expression oestrogenic compounds
- fundulus heteroclitus aromatase mrna expression
- benzo a pyrene exposure
- chorionic gonadotropin gene expression pyrene induction
- benzo a pyrene cellular expression
- altered gene expression
- benzo a pyrene dna adduct formation
- benzo a pyrene oxygenated pahs
- benzo a pyrene scophthalmus maximus
- gene expression follicle depletion
- aromatase genes gender types
- aromatase gene expression melanotaenia fluviatilis
- benzo a pyrene cytochrome p4501a
- benzo a pyrene mixture effects
- benzo a pyrene cardiovascular development
- benzo a pyrene zebrafish embryos