Prenatal Exposure to Polycyclic Aromatic Hydrocarbons, Benzo[a]pyreneDNA Adducts, and Genomic DNA Methylation in Cord Blood

JB Herbstman, D Tang, D Zhu, L Qu… - Environmental …, 2012 - ehp.niehs.nih.gov
… The distributions of PAH measurements in air and urine, BaP–DNA adducts, and DNA
methylation in our study population are described in Table 1. Median BaP and total PAH …

Benzo [a] pyrene decreases global and gene specific DNA methylation during zebrafish development

X Fang, C Thornton, BE Scheffler, KL Willett - Environmental toxicology and …, 2013 - Elsevier
… and gene specific DNA methylation status in zebrafish larvae. … DNA methylation status in
zebrafish larvae at environmentally relevant concentrations. The reduction in DNA methylation

[HTML][HTML] Dynamic changes of DNA methylation induced by benzo (a) pyrene in cancer

H Wang, B Liu, H Chen, P Xu, H Xue, J Yuan - Genes and Environment, 2023 - Springer
hypermethylation, resulting in cancer initiation and progression. Here we summarized …
changes in DNA methylation in BaP exposure, and revealed the methylation of DNA plays a …

Epigenome-wide DNA methylation signature of benzo [a] pyrene exposure and their mediation roles in benzo [a] pyrene-associated lung cancer development

H Meng, G Li, W Wei, Y Bai, Y Feng, M Fu… - Journal of hazardous …, 2021 - Elsevier
… Our results highlight DNA methylation alterations as potential … -wide DNA methylation
changes associated with B[a]P exposure is still unknown and the extent to which DNA methylation

[HTML][HTML] Influence of benzo (a) pyrene on different epigenetic processes

B Bukowska, P Sicińska - International Journal of Molecular Sciences, 2021 - mdpi.com
… The results showed the tissue specificity of global DNA methylation, ie, the total genomic
DNA methylation level was significantly decreased in the blood and liver but not in the pancreas…

Effects on specific promoter DNA methylation in zebrafish embryos and larvae following benzo [a] pyrene exposure

J Corrales, X Fang, C Thornton, W Mei… - … and Physiology Part C …, 2014 - Elsevier
DNA methylation could be involved in the BaP-induced toxicity (Fang et al., 2013a). Therefore,
we hypothesized that BaP alters DNA methylation … of DNA (DNA methylation) or histones (…

Association of environmental benzo [a] pyrene exposure and DNA methylation alterations in hepatocellular carcinoma: a Chinese case–control study

M Tian, B Zhao, J Zhang, FL Martin, Q Huang… - Science of The Total …, 2016 - Elsevier
… risk factors [eg, benzo[a]pyrene (B[a]P), … , serum DNA methylation of TSGs was quantified
using high-resolution melting (HRM) analysis. Our results clearly indicate elevated methylation

Toxicological effects of benzo [a] pyrene on DNA methylation of whole genome in ICR mice

L Zhao, S Zhang, X An, W Tan, D Pang… - Cellular and molecular …, 2015 - cellmolbiol.org
… in DNA methylation of whole genome due to benzo[a] pyrene exposure. In this study, the
effects of benzo[a] pyrene on DNA methylation … acute exposure of benzo[a]pyrene to ICR mice. …

Embryonic exposure to benzo (a) pyrene inhibits reproductive capability in adult female zebrafish and correlation with DNA methylation

D Gao, J Lin, K Ou, Y Chen, H Li, Q Dai, Z Yu… - Environmental …, 2018 - Elsevier
hypermethylation of promoter DNA is generally related to gene silencing (Vandegehuchte
and Janssen, 2011). In this study, the DNA methylation … , since DNA methylation is heritable in …

The effect of benzo [alpha] pyrene on DNA methylation and telomerase activity in human normal and cancer cells

R Zarei, D Moghadam, MM Sarabi, F Naghibalhossaini - Toxicology in Vitro, 2022 - Elsevier
DNA methylation in human normal and cancer cells. … DNA methylation changes are two
hallmarks of cancer cells. Previous studies have demonstrated that the global DNA methylation