DNA methylation levels in normal and chemically-transformed mouse 3T3 cells
ES Diala, RM Hoffman - Biochemical and Biophysical Research …, 1982 - Elsevier
… to cytosine base ratios in their total genomic DNA. The DNA methylation levels appear to
be approximately … Summary of extent of DNA methylation in normal and chemically-transformed …
be approximately … Summary of extent of DNA methylation in normal and chemically-transformed …
[Effects of cell malignant transformation induced by benzo [a] pyrene on DNA methylation transferases].
W Deng, M Yang, Z Zhang, M Wu - Wei Sheng yan jiu= Journal of …, 2013 - europepmc.org
… To investigate the expression level and enzymatic activity of DNA methylation transferases
(dnmts) in mouse embryonic fibroblast malignant transformed cells induced by benzopyrene (…
(dnmts) in mouse embryonic fibroblast malignant transformed cells induced by benzopyrene (…
Effects of benzo[a]pyrene on mouse germ cells: heritable DNA mutation, testicular cell hypomethylation and their interaction with nucleotide excision repair
RWL Godschalk, N Verhofstad, M Verheijen… - Toxicology …, 2015 - academic.oup.com
… in DNA methylation in testicular cells, and to investigate the relationship between these
endpoints, we orally treated DNA repair deficient Xpc −/− and DNA … global DNA methylation by …
endpoints, we orally treated DNA repair deficient Xpc −/− and DNA … global DNA methylation by …
Zebrafish as a model to study the role of DNA methylation in environmental toxicology
… In this review, recent insights in DNA methylation during zebra fish development are … study
the role of DNA methylation in environmental toxicology. Differences exist in DNA methylation …
the role of DNA methylation in environmental toxicology. Differences exist in DNA methylation …
Abnormal methylation of spermatozoa induced by benzo (a) pyrene in rats
CM Zhang, ZX Sun, ZL Wang, JS Chen… - Human & …, 2019 - journals.sagepub.com
… We conclude that BaP can cause significant changes in the DNA methylation of spermatozoa,
mainly hypomethylation, and these changes are associated with embryonic development, …
mainly hypomethylation, and these changes are associated with embryonic development, …
The Role of Oxidative Stress and DNA Hydroxymethylation in the Pathogenesis of Benzo [a] pyrene‐Impaired Reproductive Function in Male Mice
Y Gan, X Zhang, P Cai, L Zhao, K Liu… - Environmental …, 2024 - Wiley Online Library
… Then, the reproductive function, alterations of oxidative stress, DNA methylation, and DNA
… Furthermore, a significant induction of hydroxymethylation and inhibition of methylation were …
… Furthermore, a significant induction of hydroxymethylation and inhibition of methylation were …
Benzo [a] pyrene effects on glycine N-methyltransferase mRNA expression and enzyme activity in Fundulus heteroclitus embryos
X Fang, W Dong, C Thornton, KL Willett - Aquatic toxicology, 2010 - Elsevier
… Benzo[a]pyrene (BaP) is a ubiquitous environmental polycyclic … involved in regulation of
DNA methylation, and altered GNMT … embryonic toxicities and DNA methylation changes. …
DNA methylation, and altered GNMT … embryonic toxicities and DNA methylation changes. …
Integrated epigenetics, transcriptomics, and metabolomics to analyze the mechanisms of benzo [a] pyrene neurotoxicity in the hippocampus
J Wang, CL Li, BJ Tu, K Yang, TT Mo… - Toxicological …, 2018 - academic.oup.com
… In the present study, we investigated the global effect of B[a]P on DNA methylation patterns,
noncoding RNAs (ncRNAs) expression, coding RNAs expression, and metabolites in the rat …
noncoding RNAs (ncRNAs) expression, coding RNAs expression, and metabolites in the rat …
Protective effect of Yishen Tongluo Recipe against benzo (a) pyrene-induced sperm DNA methylation changes in male rats
ZX Sun, CM Zhang, PC Li, JS Chen… - Zhonghua nan ke xue …, 2019 - europepmc.org
… DNA methylation in male rats exposed to benzo(a)pyrene (BaP). … The methylated DNA
immunoprecipitation sequencing (… detect the whole-genome DNA methylation in different groups. …
immunoprecipitation sequencing (… detect the whole-genome DNA methylation in different groups. …
Transcriptomic changes in zebrafish embryos and larvae following benzo [a] pyrene exposure
X Fang, J Corrales, C Thornton, T Clerk… - Toxicological …, 2015 - academic.oup.com
… DNA methylation typically inhibits gene expression and gene body DNA methylation also
regulates transcription, we hypothesized that BaP-induced aberrant DNA methylation patterns …
regulates transcription, we hypothesized that BaP-induced aberrant DNA methylation patterns …