Application of the margin-of-exposure (MoE) approach to substances in food that are genotoxic and carcinogenic eg: benzo [a] pyrene and polycyclic aromatic …
D Benford, M DiNovi, RW Setzer - Food and Chemical Toxicology, 2010 - Elsevier
… Tumors and DNA adducts in mice exposed to benzo[a]pyrene and coal … benzo[a]pyrene
for 2 years (gavage studies). Implications for human cancer risks associated with oral exposure …
for 2 years (gavage studies). Implications for human cancer risks associated with oral exposure …
Cumulative metabolic effects of low-dose benzo(a)pyrene exposure on human cells
… exposure at environmental dosage, we utilized the human SMMC-7721 cell-based B[a]P
exposure … were influenced by prolonged B[a]P exposure. Notably, the metabolic effects of B[a]P …
exposure … were influenced by prolonged B[a]P exposure. Notably, the metabolic effects of B[a]P …
Biomarkers and bioaccumulation of clam Ruditapes philippinarum in response to combined cadmium and benzo [α] pyrene exposure
L Wang, L Pan, N Liu, D Liu, C Xu, J Miao - Food and chemical toxicology, 2011 - Elsevier
… clams Ruditapes philippinarum exposed to cadmium (Cd, 15μg/L) and benzo[α]pyrene (BaP, …
, Zn-SOD increased remarkably in the clams exposed to combined pollutants. In this study, …
, Zn-SOD increased remarkably in the clams exposed to combined pollutants. In this study, …
Chronic exposure to the carcinogenic compound benzo [a] pyrene induces larger and phenotypically different atherosclerotic plaques in ApoE-knockout mice
… In the B[a]P-exposed animals advanced plaques contained … exposed to PAHs on a daily
basis, mainly via ingestion of contaminated foods and inhalation of polluted air. Benzo[a]pyrene (…
basis, mainly via ingestion of contaminated foods and inhalation of polluted air. Benzo[a]pyrene (…
Exposure of Japanese medaka (Oryzias latipes) to benzo [a] pyrene suppresses immune function and host resistance against bacterial challenge
EA Carlson, Y Li, JT Zelikoff - Aquatic Toxicology, 2002 - Elsevier
… at 48 h post-BaP exposure for later determination of antibody-… or condition factors, a single
exposure to a relatively low dose of … of BaP exposure/effects in exposed feral populations. …
exposure to a relatively low dose of … of BaP exposure/effects in exposed feral populations. …
Distribution of benzo[a]pyrene in pregnant rats following inhalation exposure and a comparison with similar data obtained with pyrene
JR Withey, J Shedden, FCP Law… - Journal of Applied …, 1993 - Wiley Online Library
… -min inhalation exposure to a micronized aerosol of pyrene (a model … benzo[a]pyrene (a
PAH that is probably carcinogenic to humans) has been evaluated following inhalation exposure …
PAH that is probably carcinogenic to humans) has been evaluated following inhalation exposure …
Review on proteomic analyses of benzo [a] pyrene toxicity
N Verma, M Pink, AW Rettenmeier… - …, 2012 - Wiley Online Library
… Exposure to BaP elicits many adverse biological effects, including tumor formation, … In
addition to the genetic damage caused by BaP exposure, several studies have indicated the …
addition to the genetic damage caused by BaP exposure, several studies have indicated the …
Altered gene expression: A mechanism for reproductive toxicity in zebrafish exposed to benzo [a] pyrene
JL Hoffmann, JT Oris - Aquatic Toxicology, 2006 - Elsevier
… effect of exposure to waterborne benzo[a]pyrene (B[a]… exposure to B[a]P. A reduction in
total egg output was observed in B[a]P exposed fish as well as a decrease in OSI in fish exposed …
total egg output was observed in B[a]P exposed fish as well as a decrease in OSI in fish exposed …
[HTML][HTML] Oral exposure to environmental pollutant benzo [a] pyrene impacts the intestinal epithelium and induces gut microbial shifts in murine model
C Ribière, P Peyret, N Parisot, C Darcha… - Scientific reports, 2016 - nature.com
… of benzo[a]pyrene (BaP, most toxic PAH) oral exposure on … BaP oral exposure significantly
altered the composition and … environment following BaP oral exposure. Therefore, under …
altered the composition and … environment following BaP oral exposure. Therefore, under …
Acute benzo[a]pyrene exposure induced oxidative stress, neurotoxicity and epigenetic change in blood clam Tegillarca granosa
B Guo, D Feng, Z Xu, P Qi, X Yan - Scientific Reports, 2021 - nature.com
… exposure on the blood clams under laboratory conditions, as well as the potential mechanisms.
Acute Bap exposure … hypomethylation was observed in Bap exposed the blood clam. The …
Acute Bap exposure … hypomethylation was observed in Bap exposed the blood clam. The …