Benzo[a]pyrene—Environmental Occurrence, Human Exposure, and Mechanisms of Toxicity
B Bukowska, K Mokra, J Michałowicz - International journal of molecular …, 2022 - mdpi.com
… B[a]P mainly contributed to cancer development in children in all schools tested. Similarly, the
… morphological and physiological abnormalities in the zebrafish skeleton (head, spine, and …
… morphological and physiological abnormalities in the zebrafish skeleton (head, spine, and …
The role of the aryl hydrocarbon receptor pathway in mediating synergistic developmental toxicity of polycyclic aromatic hydrocarbons to zebrafish
SM Billiard, AR Timme-Laragy… - Toxicological …, 2006 - academic.oup.com
… of zebrafish (… of zebrafish AHR2 and CYP1A proteins during development. We observed
that while knock down of AHR2 reduces cardiac toxicity of BNF combined with ANF to zebrafish …
that while knock down of AHR2 reduces cardiac toxicity of BNF combined with ANF to zebrafish …
Protective effects of genistein and estradiol on PAHs-induced developmental toxicity in zebrafish embryos
X Ren, F Lu, Y Cui, X Wang, C Bai… - Human & …, 2012 - journals.sagepub.com
… In the present study, benzo(a)pyrene (B(a)P) and benzo(k)… and combined developmental
toxicity using zebrafish embryos as … and mortality in developing zebrafish embryos. The toxicity …
toxicity using zebrafish embryos as … and mortality in developing zebrafish embryos. The toxicity …
Zebrafish CYP1A expression in transgenic Caenorhabditis elegans protects from exposures to benzo [a] pyrene and a complex polycyclic aromatic hydrocarbon …
… to the developmental exposure, we also performed an exposure beginning at the fourth
larval stage (L4) to determine organismal reproductive toxicity, in the absence of developmental …
larval stage (L4) to determine organismal reproductive toxicity, in the absence of developmental …
Comparative in vitro metabolism of benzo [a] pyrene by recombinant zebrafish CYP1A and liver microsomes from β-naphthoflavone-treated rainbow trout
CL Miranda, WG Chung, JL Wang-Buhler… - Aquatic Toxicology, 2006 - Elsevier
… zebrafish CYP1A converts benzo[a]pyrene to a diol epoxide that binds to DNA. Panel A: HPLC
profile after incubation of calf thymus DNA with zebrafish … 3- 3 H]-benzo[a]pyrene. Note the …
profile after incubation of calf thymus DNA with zebrafish … 3- 3 H]-benzo[a]pyrene. Note the …
Chronic exposure to environmental concentrations of benzo [a] pyrene causes multifaceted toxic effects of developmental compromise, redox imbalance, and …
… Our study addresses these gaps by evaluating developmental abnormalities, growth disruptions,
… This comprehensive approach provides valuable insights into the early developmental …
… This comprehensive approach provides valuable insights into the early developmental …
Benzo (a) pyrene decreases brain and ovarian aromatase mRNA expression in Fundulus heteroclitus
… study was to investigate the potential for benzo(a)pyrene (BaP), a … effects of exposure at
different developmental stages, we aimed … When protogynic fish like zebrafish were exposed to …
different developmental stages, we aimed … When protogynic fish like zebrafish were exposed to …
Generation and application of a novel transgenic zebrafish line Tg (cyp1a: mCherry) as an in vivo assay to sensitively monitor PAHs and TCDD in the environment
… In this study, an in vivo approach was developed and applied to detect the contamination
level of the PAHs and TCDD in the environment. Our purpose was to create a stable, sensitive, …
level of the PAHs and TCDD in the environment. Our purpose was to create a stable, sensitive, …
Effect of Benzo (a) pyrene on the craniofacial development of zebrafish
B O'Connor - 2015 - dc.uwm.edu
… is to develop exposure windows to identify the developmental process benzo(a)pyrene is
disrupting. … deformities in zebrafish associated with exposure to benzo(a)pyrene resulting in a …
disrupting. … deformities in zebrafish associated with exposure to benzo(a)pyrene resulting in a …
Reproductive and Multigenerational Effects of Dietary Benzo [A] Pyrene Exposure in Zebrafish
M White - 2014 - egrove.olemiss.edu
… Dietary benzo(a)pyrene intake during pregnancy and birth weight: Associations … Benzo[a]pyrene
decreases global and gene specific DNA methylation during zebrafish development. …
decreases global and gene specific DNA methylation during zebrafish development. …