Effects of benzo (a) pyrene exposure on killifish (Fundulus heteroclitus) aromatase activities and mRNA

MR Patel, BE Scheffler, L Wang, KL Willett - Aquatic Toxicology, 2006 - Elsevier
… Estrogens play important roles in the development, growth, … a number of developmental
and reproductive events … by the higher sensitivity of the juvenile zebrafish or the much higher …

Effect‐directed analysis of Elizabeth River porewater: Developmental toxicity in zebrafish (Danio rerio)

M Fang, GJ Getzinger, EM Cooper… - Environmental …, 2014 - Wiley Online Library
… to the porewater displayed acute developmental toxicity and … as the pericardial area in
embryonic zebrafish. The most toxic … (eg, benzo[a]pyrene and indeno[1,2,3‐cd]pyrene). Addition of …

… zebrafish larvae identifies iron-dependent mitochondrial dysfunction as a possible key event of NAFLD progression induced by benzo [a] pyrene/ethanol co-exposure

M Imran, F Chalmel, O Sergent, B Evrard… - Cell Biology and …, 2023 - Springer
… To this aim, we used our recently developed model of HFD fed zebrafish larva, proven to
be reliable to human models, in which B[a]P/ethanol co-exposure was involved in NAFLD …

Mutational spectra of benzo [a] pyrene and MeIQx in rpsL transgenic zebrafish embryos

K Amanuma, S Tone, H Saito, T Shigeoka… - … /Genetic Toxicology and …, 2002 - Elsevier
zebrafish (Brachydanio rerio) mutation assay, we treated the embryos with benzo[a]pyrene
(B[… This study showed that transgenic zebrafish may be a useful tool for detecting mutagens in …

Synergistic induction of AHR regulated genes in developmental toxicity from co-exposure to two model PAHs in zebrafish

AR Timme-Laragy, CJ Cockman, CW Matson… - Aquatic toxicology, 2007 - Elsevier
… While our studies did not include metabolite analysis, our interpretation of these data is
supported by microcosm studies examining metabolism of the PAH benzo(a)pyrene (BaP) with co…

Ancestral benzo [a] pyrene exposure affects bone integrity in F3 adult fish (Oryzias latipes)

F Seemann, CB Jeong, G Zhang, MT Wan, B Guo… - Aquatic Toxicology, 2017 - Elsevier
Benzo[a]pyrene (BaP) at an environmentally relevant concentration (1 μg/L) has previously
been shown to affect bone development in a transgenerational manner in F3 medaka (…

Biotransformation in the zebrafish embryo–temporal gene transcription changes of cytochrome P450 enzymes and internal exposure dynamics of the AhR binding …

A Kühnert, C Vogs, B Seiwert, S Aulhorn… - Environmental …, 2017 - Elsevier
… Therefore, we conclude that the developmental stage of the zebrafish embryo rather than
the exposure duration determines the delayed induction of gene transcription and the following …

[HTML][HTML] Transcriptome aberration associated with altered locomotor behavior of zebrafish (Danio rerio) caused by Waterborne Benzo [a] pyrene

Y Zhou, Q Kong, Z Lin, J Ma, H Zhang - Ecotoxicology and environmental …, 2021 - Elsevier
… of zebrafish (Danio rerio), however, how it affect the locomotor behavior of adult zebrafish
molecular mechanisms of the affected locomotor behavior of zebrafish by B[a]P based on …

Benzo (a) pyrene-induced cytochrome p4501A expression of four freshwater fishes (Oryzias latipes, Danio rerio, Cyprinus carpio, and Zacco platypus)

JW Lee, HG Yoon, SK Lee - Environmental Toxicology and Pharmacology, 2015 - Elsevier
… To compare susceptibility, dose- and time-dependent CYP1A induction at the mRNA and
protein levels in response to benzo(a)pyrene (BaP) exposure was analyzed. At the mRNA level…

Basal and benzo [a] pyrene-induced expression profile of phase I and II enzymes and ABC transporter mRNA in the early life stage of Chinese rare minnows …

L Yuan, B Lv, J Zha, W Wang, Z Wang - Ecotoxicology and environmental …, 2014 - Elsevier
… In contrast, the developmental toxicity of some tetracyclic PAHs (eg, pyrene and benz[a]anthracene)
and pentacyclic PAHs (eg, BaP) requires a functional AHR, but the tetracyclic …