Biology and function of adipose tissue macrophages, dendritic cells and B cells

S Ivanov, J Merlin, MKS Lee, AJ Murphy… - Atherosclerosis, 2018 - Elsevier
The increasing incidence of obesity and its socio-economical impact is a global health issue
due to its associated co-morbidities, namely diabetes and cardiovascular disease
[[1],[2],[3],[4],[5]]. Obesity is characterized by an increase in adipose tissue, which promotes
the recruitment of immune cells resulting in low-grade inflammation and dysfunctional
metabolism. Macrophages are the most abundant immune cells in the adipose tissue of
mice and humans. The adipose tissue also contains other myeloid cells (dendritic cells (DC) …
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