Theoretical analysis of protein concentration determination using biosensor technology under conditions of partial mass transport limitation

LLH Christensen - Analytical biochemistry, 1997 - Elsevier
… from inactransport coefficient exists when mass transport is to… limiting (1, 7, 8). To find
conditions of partial samples. With the BIAcore biosensor technology it is mass transport limitation

Concentration measurement of unpurified proteins using biosensor technology under conditions of partial mass transport limitation

PM Richalet-Sécordel, N Rauffer-Bruyère… - Analytical …, 1997 - Elsevier
… We describe a new biosensor method for measuring TABLE 3 … be totally limited by mass
transport at a flow rate of 15 ml/min. This represents an important limitation of sured as indicated …

… rate constants of interacting biomolecules: an analytical solution to the theory for kinetic and mass transport limitations in biosensor technology and its experimental …

K Sigmundsson, G Másson, R Rice, N Beauchemin… - Biochemistry, 2002 - ACS Publications
… ) technology. The method relies on changes in binding rates with varying flow rates under
conditions of partial mass transport, … , under partial mass transport limitations. This solution can …

Mechanistic challenges and advantages of biosensor miniaturization into the nanoscale

L Soleymani, F Li - ACS sensors, 2017 - ACS Publications
… and mass transport limitations that must be considered in reducing the biosensing length
scale … While these considerations are applicable to various classes of biosensors, we limit our …

The role of mass transport limitation and surface heterogeneity in the biophysical characterization of macromolecular binding processes by SPR biosensing

P Schuck, H Zhao - Surface plasmon resonance: methods and protocols, 2010 - Springer
… the kinetic analysis of SPR biosensor data for the determination of … transport limitations and
the heterogeneity of the surface sites. These problems are intrinsic to the use of a biosensor

Detection limits for nanoscale biosensors

PE Sheehan, LJ Whitman - Nano letters, 2005 - ACS Publications
… We conclude that without directed transport of biomolecules, … explicitly examine mass
transport effects on biosensing at the … limits for bioassays are likely an analyte transport limitation, …

Performance limitations for nanowire/nanoribbon biosensors

NK Rajan, X Duan, MA Reed - Wiley Interdisciplinary Reviews …, 2013 - Wiley Online Library
… factor for the sensor response rate (mass-transport limited regime), … transport limitation, but
the increase of the signal with time remained linear. As expected, the reported detection limits

Absolute quantification of microRNAs based on mass transport limitation under a laminar flow SPR system

K Li, N An, L Wu, M Wang, F Li, L Li - Biosensors and Bioelectronics, 2024 - Elsevier
… ) biosensor for quantifying miRNAs without standard. We introduced the mass transport limitation
… condition for triggering MTL on the SPR biosensor. We demonstrated that probes of 22–…

Advances, limitations, and prospects of biosensing technology for detecting phytopathogenic bacteria

Q Ali, H Zheng, MJ Rao, M Ali, A Hussain, MH Saleem… - Chemosphere, 2022 - Elsevier
… In addition, we extensively review the natural potential of different biosensors for plant bacterial
detection. The specificity of biosensors can be greatly improved by using antibodies, DNA…

Development of biosensor technologies for analysis of environmental contaminants

X Wang, X Lu, J Chen - Trends in Environmental Analytical Chemistry, 2014 - Elsevier
… We discuss the future trends, limitations and challenges of biosensors for environmental …
the assembling of novel biosensing systems as electron transport mediator and support matrix …