… Thus, despite the ascendency of effective and convenient once-daily LAMA bronchodilator
therapy (tiotropium bromide) in clinical practice for both reversal of bronchoconstriction and …

… In the current SHINE study, we sought to confirm the “rule of combination” [12] that dual
bronchodilation with QVA149 will provide additional therapeutic benefits compared to the …

… of magnesium with respect to standard bronchodilators, and conflicting conclusions have led
to … as an adjunct to standard bronchodilator therapy in AECOPD patients presenting to the …

… open and closed dual-combination bronchodilators in patients with moderate-to-very severe
COPD who were eligible to receive maintenance bronchodilator therapy. Four endpoints, …

… of one or more long-acting bronchodilators for patients with moderate to … bronchodilator
therapy. The objective of this article is to review clinical data on combined bronchodilator therapy …

… UMEC is a highly effective bronchodilator that leads to improved lung function when
administered as a single bronchodilator on top of FF in subjects with fully reversible, uncontrolled/…

… groups (table 1). The study population had clinically significant COPD, with mean predicted
post-bronchodilator … Overall, the mean predicted FEV 1 after use of bronchodilators was 45·4…

… Despite the availability of effective bronchodilator therapies, ~90% of … mono-therapy or
long-acting β 2 -agonist (LABA) monotherapy, and step-up therapy to a long-acting bronchodilator …

… use of combination bronchodilator therapy in patients with … that certain combinations of
bronchodilators may prevent … the clinical effect of combining bronchodilators in the treatment of …

Introduction The fixed-dose, long-acting bronchodilator combination of umeclidinium/vilanterol
(UMEC/VI) has not previously been compared with a combination of a long-acting …