A 28-day, randomized, double-blind, placebo-controlled, parallel group study of nebulized revefenacin in patients with chronic obstructive pulmonary disease
KK Pudi, CN Barnes, EJ Moran, B Haumann… - Respiratory …, 2017 - Springer
… Thus, despite the ascendency of effective and convenient once-daily LAMA bronchodilator
therapy (tiotropium bromide) in clinical practice for both reversal of bronchoconstriction and …
therapy (tiotropium bromide) in clinical practice for both reversal of bronchoconstriction and …
Dual bronchodilation with QVA149 versus single bronchodilator therapy: the SHINE study
ED Bateman, GT Ferguson, N Barnes… - European …, 2013 - Eur Respiratory Soc
… In the current SHINE study, we sought to confirm the “rule of combination” [12] that dual
bronchodilation with QVA149 will provide additional therapeutic benefits compared to the …
bronchodilation with QVA149 will provide additional therapeutic benefits compared to the …
… sulphate as an adjuvant therapy in acute exacerbations of chronic obstructive pulmonary disease: a single centre, randomised, double-blinded, parallel group …
S Mukerji, B Shahpuri, B Clayton-Smith… - The New Zealand …, 2015 - search.proquest.com
… of magnesium with respect to standard bronchodilators, and conflicting conclusions have led
to … as an adjunct to standard bronchodilator therapy in AECOPD patients presenting to the …
to … as an adjunct to standard bronchodilator therapy in AECOPD patients presenting to the …
Comparative efficacy of combination bronchodilator therapies in COPD: a network meta-analysis
EL Huisman, SM Cockle, AS Ismaila… - … Journal of Chronic …, 2015 - Taylor & Francis
… open and closed dual-combination bronchodilators in patients with moderate-to-very severe
COPD who were eligible to receive maintenance bronchodilator therapy. Four endpoints, …
COPD who were eligible to receive maintenance bronchodilator therapy. Four endpoints, …
Bronchodilator combination therapy for the treatment of chronic obstructive pulmonary disease
S Sethi, C Cote - Current Clinical Pharmacology, 2011 - ingentaconnect.com
… of one or more long-acting bronchodilators for patients with moderate to … bronchodilator
therapy. The objective of this article is to review clinical data on combined bronchodilator therapy …
therapy. The objective of this article is to review clinical data on combined bronchodilator therapy …
A phase IIb, randomised, parallel-group study: the efficacy, safety and tolerability of once-daily umeclidinium in patients with asthma receiving inhaled corticosteroids
… UMEC is a highly effective bronchodilator that leads to improved lung function when
administered as a single bronchodilator on top of FF in subjects with fully reversible, uncontrolled/…
administered as a single bronchodilator on top of FF in subjects with fully reversible, uncontrolled/…
… furoate and vilanterol versus vilanterol only for prevention of exacerbations of COPD: two replicate double-blind, parallel-group, randomised controlled trials
MT Dransfield, J Bourbeau, PW Jones… - The Lancet …, 2013 - thelancet.com
… groups (table 1). The study population had clinically significant COPD, with mean predicted
post-bronchodilator … Overall, the mean predicted FEV 1 after use of bronchodilators was 45·4…
post-bronchodilator … Overall, the mean predicted FEV 1 after use of bronchodilators was 45·4…
Umeclidinium/vilanterol as step-up therapy from tiotropium in patients with moderate COPD: a randomized, parallel-group, 12-week study
EM Kerwin, CJ Kalberg, DV Galkin… - … Journal of Chronic …, 2017 - Taylor & Francis
… Despite the availability of effective bronchodilator therapies, ~90% of … mono-therapy or
long-acting β 2 -agonist (LABA) monotherapy, and step-up therapy to a long-acting bronchodilator …
long-acting β 2 -agonist (LABA) monotherapy, and step-up therapy to a long-acting bronchodilator …
Combination inhaled bronchodilator therapy in the management of chronic obstructive pulmonary disease
J Nichols - … Journal of Human Pharmacology and Drug Therapy, 2007 - Wiley Online Library
… use of combination bronchodilator therapy in patients with … that certain combinations of
bronchodilators may prevent … the clinical effect of combining bronchodilators in the treatment of …
bronchodilators may prevent … the clinical effect of combining bronchodilators in the treatment of …
Dual bronchodilator therapy with umeclidinium/vilanterol versus tiotropium plus indacaterol in chronic obstructive pulmonary disease: a randomized controlled trial
C Kalberg, D O'Dell, D Galkin, A Newlands, WA Fahy - Drugs in R&D, 2016 - Springer
Introduction The fixed-dose, long-acting bronchodilator combination of umeclidinium/vilanterol
(UMEC/VI) has not previously been compared with a combination of a long-acting …
(UMEC/VI) has not previously been compared with a combination of a long-acting …