Liberty Asthma QUEST: phase 3 randomized, double-blind, placebo-controlled, parallel-group study to evaluate dupilumab efficacy/safety in patients with uncontrolled …

WW Busse, JF Maspero, KF Rabe, A Papi… - … in therapy, 2018 - Springer
… change from baseline in pre-bronchodilator FEV 1 at week 12. … to week 12 in pre-bronchodilator
FEV 1 . Additional lung … 75%, post-bronchodilator FEV 1 , and post-bronchodilator slope …

Comparison of the anticholinergic bronchodilator ipratropium bromide with metaproterenol in chronic obstructive pulmonary disease: a 90-day multi-center study

DP Tashkin, K Ashutosh, ER Bleecker, EJ Britt… - The American journal of …, 1986 - Elsevier
… achievable bronchodilation, whereas serial doses of albuterol … blind, randomly ordered,
parallel-group study design, we found … manner to a comparable group of patients. The superior …

[HTML][HTML] Safety and efficacy of dual bronchodilation with QVA149 in COPD patients: the ENLIGHTEN study

R Dahl, KR Chapman, M Rudolf, R Mehta, P Kho… - Respiratory …, 2013 - Elsevier
… was included to patients' established background COPD therapy, for example, daily ICS.
The short-acting bronchodilator salbutamol (albuterol) was provided for rescue use throughout …

Pharmacoeconomic evaluation of a combination of ipratropium plus albuterol compared with ipratropium alone and albuterol alone in COPD

M Friedman, CW Serby, SS Menjoge, JD Wilson… - Chest, 1999 - Elsevier
… with bronchodilator therapy in most COPD patients. … , parallel group studies that were
conducted to evaluate the long-term efficacy and safety of ipratropium combined with albuterol in a …

Combined bronchodilators (tiotropium plus olodaterol) for patients with chronic obstructive pulmonary disease

WH Ramadan, WK Kabbara, GM El Khoury… - … Journal of Chronic …, 2015 - Taylor & Francis
bronchodilation than single drugs alone. In two randomized, double-blind, parallel-group, …
As a result, they are likely to be on more than one bronchodilator therapy to treat airflow …

Lung function efficacy and symptomatic benefit of olodaterol once daily delivered via Respimat® versus placebo and formoterol twice daily in patients with GOLD 2–4 …

A Koch, E Pizzichini, A Hamilton, L Hart… - … journal of chronic …, 2014 - Taylor & Francis
… , placebo-controlled, parallel-group, Phase III studies investigated … The first available
long-acting bronchodilators (such as the … More recently, bronchodilators with a longer duration of …

Effect of bronchodilation, exercise training, and behavior modification on symptoms and physical activity in chronic obstructive pulmonary disease

T Troosters, F Maltais, N Leidy, KL Lavoie… - American Journal of …, 2018 - atsjournals.org
… , placebo-controlled, parallel-group trial in patients with COPD (… 12 in all groups receiving
SMBM plus bronchodilator therapy … in the groups receiving SMBM plus bronchodilator therapy

Salmeterol plus theophylline combination therapy in the treatment of COPD

RL ZuWallack, DA Mahler, D Reilly, N Church… - Chest, 2001 - Elsevier
… This randomized, double-blind, double-dummy, parallel-group trial compared the efficacy …
has been observed previously with inhaled bronchodilator therapy. Similarly, the improvement …

Continuous and on demand use of bronchodilators in patients with non-steroid dependent asthma and chronic bronchitis: four-year follow-up randomized controlled …

CP van Schayck, E Dompeling… - British Journal of …, 1995 - bjgp.org
bronchodilator therapy. At the start of the four-year study, patients were randomly assigned
to one of two parallel treatment groups… ) between the two parallel treatment groups was 40 ml …

Inhalation by nebulization of albuterol-ipratropium combination (Dey combination) is superior to either agent alone in the treatment of chronic obstructive pulmonary …

…, S Linberg, D Dey Combination Solution Study Group - Respiration, 1998 - karger.com
… Combination bronchodilator therapy for chronic obstructive … the effectiveness of an
albuterol-ipratropium solution aerosol … in an 8-week parallel-group experience in which to …