… covalent binding interactions. Hence, we initiated this covalent binder database (cBinderDB)…
A text mining toolkit was developed to systematically collect, validate and annotate covalent …

… (27) Recently, Hou et al. established the CovalentInDB database of 4511 covalent inhibitors
for 280 protein targets, among which covalent binding mechanisms of 842 compounds (…

… are covalent binders because they form covalent bonds with the side chains of the amino acid
residues in the binding … the decommissioned cBinderDB database of 527 covalent binders …

… , cBinderDB is not accessible anymore. In this study, we developed Covalent Inhibitor
Database (… residues and inherent covalent binding sites and (ii) small covalent inhibitors that …

… Herein, we report CovPDB, the first database solely dedicated to high-resolution … a covalent
bonding mechanism not until long after their market approval (1,2). Conversely, covalent …

… [22,23], and they did well in simulating the covalent bonds between a protein and a metal
species; our work focuses on common … We will update the BCDE database when possible. …

… Covalent binding can overcome this challenge in some … was cBinderDB [Citation19],
containing data from 527 covalent binders and 190 related protein targets, however, this database …

… used DeLinker for fragment replacement in the covalent binding portion of covalent
adducts. … Databases used in this study could be accessed as follows: ChEMBL(https://www.ebi.ac.uk/…

… to combine a non-covalent binding scaffold with an … databases to integrate published
covalent modifiers to better serve the demand of structure-based virtual screening: cBinderDB, 10 …

… of the targeted proteins by forming covalent bonds with nucleophilic amino acid residues [1]. …
Statistics for covalent binders available in the CBinder database, chemical structure of the …