cDNA cloning and expression of brain and ovary aromatase in tilapia, Oreochromis mossambicus
M Cruz, AVM Canario - … Symposium on the Reproductive Physiology of …, 2000 - lifewatch.be
The cDNA for P450 aromatase, an essential enzyme for estrogen biosynthesis, was cloned
from the brain and ovary of Oreochromis mossambicus. The brain form shares 58% identity
with the ovarian form and shows higher sequence identity to Carassius auratus brain
aromatase (66%). A single transcript for the two aromatase forms has been found specific for
the tissues from which they were cloned. Both enzymes appear to be expressed in embryos
from 5 days post fertilisation
from the brain and ovary of Oreochromis mossambicus. The brain form shares 58% identity
with the ovarian form and shows higher sequence identity to Carassius auratus brain
aromatase (66%). A single transcript for the two aromatase forms has been found specific for
the tissues from which they were cloned. Both enzymes appear to be expressed in embryos
from 5 days post fertilisation
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