… In this review, we address the Ca 2+ signaling pathways involved in the mechanism of …
the role of Ca 2+ influx through the recently identified TRPC channels in signaling increases in …

… the high Ca 2+ selectivity of the TRP channel shows a … the pore of the highly Ca 2+ selective
TRP channels, TRPV5 and TRPV6… Ca 2+ selectivity of TRP, but also reduce Ca 2+ influx via …

… Selected functional properties of TRP channels from each subfamily are summarized in this
… case of Ca 2+ , each ion that permeates a TRP channel possesses some intrinsic signaling …

… TRP) cation channels mediate the flux of Na + and Ca 2+ across the plasma membrane
and into the cytoplasm.1 TRP channels … , which resulted in inhibited Ca 2+ permeability and …

… summarize and discuss recent insights into the role of TRP channels in cellular Ca 2+
signaling, with particular focus on the structural determinants of TRP channel–Ca 2+ interactions. …

… Ca 2+ in the modulation of TRP ion channels remain elusive. Advances in Ca 2+ regulation
of TRP channels … of the diversified functions of TRP channels and complex Ca 2+ signaling. …

… At this point, there are no detailed structures available for the Ca 2+ impermeable TRP
channels TRPM4 and TRPM5. Limited knowledge of their pore structures is provided by …

… and made it possible to examine the hypothesis that TRP is a Ca 2+ channel/transporter (109).
The experiments of Hardie and Minke (60) revealed that the fundamental defect in the …

… to cations and their ability to modulate intracellular Ca 2+ signaling. Emerging evidence
suggests that TRP channel dysfunction significantly contributes to the physiopathology of a …

… This review was presented at the TRP 2010 symposium TRP channels: from structure to
disease, … Additionally, intracellular TRP channels may function as Ca 2+ release channels and …