… This article provides an overview of the mechanisms by which cancer chemopreventive
blocking agents increase the expression of detoxication and antioxidant genes. These agents all …

… Use of enzyme inducers as cancer chemopreventive agents … mediated in part by the
antioxidant response element (ARE), … of chemopreventive agents, including phenolic antioxidants, …

… of the antioxidant responsive element (ARE) as an element that mediates responsiveness
to chemopreventive agents Induction of drug-metabolizing and antioxidant enzymes by …

… interesting targets for chemoprevention [63]. In recent years many cancer chemopreventive
agents have been shown to induce apoptosis and conversely several tumor promoters have …

… The transcriptional activation of the chemoprotective response genes by these … called the
antioxidant responsive element (ARE) (14), or, alternatively, the electrophile response element (…

… Nrf2 is a member of basic-leucine zipper transcription factor family and has been shown to
regulate gene expression by binding to a response element, antioxidant responsive element. …

… cells with small molecule antioxidants, which appears to be … activity by certain cancer
chemopreventive agents will confer … regulatory element called the antioxidant-response element (…

Antioxidants are considered as the most promising chemopreventive agents against various
human cancers. However, some antioxidants play paradoxical roles, acting as "double-…

… of antioxidant responsive element to cancer chemoprevention. Cancer Lett. 2001;174:
103—113. … of the transcription factor Nrf2 by cancer chemopreventive agents: role of antioxidant …

… ) regulates cytoprotective genes that contain an antioxidant response element (ARE) in their
… cysteines in human Keap1 modified by the cancer chemopreventive agent sulforaphane. …