[HTML][HTML] Present and future of metastatic colorectal cancer treatment: a review of new candidate targets
G Martini, T Troiani, C Cardone, P Vitiello… - World journal of …, 2017 - ncbi.nlm.nih.gov
… made in the treatment of metastatic colorectal cancer (mCRC) due to the approval of new …
for the management of metastatic mCRC and discuss new candidate targets on the horizon. …
for the management of metastatic mCRC and discuss new candidate targets on the horizon. …
An update on the current and emerging targeted agents in metastatic colorectal cancer
E Chu - Clinical colorectal cancer, 2012 - Elsevier
… fast track mechanism with a target enrollment of 430 patients. … This study is expected to reach
its target patient enrollment in … With respect to novel candidate targeted agents, we eagerly …
its target patient enrollment in … With respect to novel candidate targeted agents, we eagerly …
[HTML][HTML] Immunotherapies and targeted therapies in the treatment of metastatic colorectal cancer
Colorectal cancer (CRC) is the third leading cause of cancer deaths, and while mortality has
largely improved in the developed world, five-year survival for metastatic disease remains …
largely improved in the developed world, five-year survival for metastatic disease remains …
[HTML][HTML] Molecular targets for the treatment of metastatic colorectal cancer
A Passardi, D Gibbons - Frontiers in Oncology, 2023 - frontiersin.org
… There is a growing need for clinical and preclinical research aimed at identifying new
targets for the selective treatment of mCRC. Among the new tumor targets under development, …
targets for the selective treatment of mCRC. Among the new tumor targets under development, …
Role of targeted agents in metastatic colorectal cancer
H Prenen, L Vecchione, E Van Cutsem - Targeted oncology, 2013 - Springer
… in CRC are the ones that target the vascular endothelial growth factor (… target the EGFR,
have been approved for the treatment of … as affecting candidate genes involved in colon tumor …
have been approved for the treatment of … as affecting candidate genes involved in colon tumor …
Anti-metastatic treatment in colorectal cancer: Targeting signaling pathways
C Lemos, U Sack, F Schmid, M Juneja… - Current …, 2013 - ingentaconnect.com
… Therefore, the EGFR pathway constitutes an important target for cancer therapy. In this …
metastasis in colon cancer has to be determined, there are already promising candidates …
metastasis in colon cancer has to be determined, there are already promising candidates …
[HTML][HTML] Treatment sequencing in metastatic colorectal cancer
DP Modest, S Pant, A Sartore-Bianchi - European Journal of Cancer, 2019 - Elsevier
… in short treatment durations compared to first-line therapy [21]. … who may become candidates
for metastatic resection and … and treatment goals are heterogeneous in first-line therapy, …
for metastatic resection and … and treatment goals are heterogeneous in first-line therapy, …
Molecular markers in the treatment of metastatic colorectal cancer
… that the goal of individualized treatment is … therapy on metastatic sites. PTEN status and
the significance of PTEN in the metastatic lesions therefore represent promising candidates …
the significance of PTEN in the metastatic lesions therefore represent promising candidates …
[HTML][HTML] Molecular-biology-driven treatment for metastatic colorectal cancer
E Lai, N Liscia, C Donisi, S Mariani, S Tolu, A Pretta… - Cancers, 2020 - mdpi.com
… of the most important therapeutic targets for mCRC treatment, and various strategies, …
treatment of patients with metastatIC colorectal cancer who are not candidatE for intensive therapy) …
treatment of patients with metastatIC colorectal cancer who are not candidatE for intensive therapy) …
Targeting vascular endothelial growth factor pathway in first-line treatment of metastatic colorectal cancer: state-of-the-art and future perspectives in clinical and …
… into the therapeutic armamentarium, since the decision of which patients are good
candidate for anti-VEGF target therapy is actually based only on gross clinical characteristics. …
candidate for anti-VEGF target therapy is actually based only on gross clinical characteristics. …
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