Low-level pyrene exposure causes cardiac toxicity in zebrafish (Danio rerio) embryos

Y Zhang, C Wang, L Huang, R Chen, Y Chen, Z Zuo - Aquatic toxicology, 2012 - Elsevier
… PAHs on vertebrate cardiovascular development and disease is unclear. Herein, we address
the cardiac developmental effects of exposure to the weak AhR agonist pyrene on the early …

[HTML][HTML] Benzo (a) pyrene and cardiovascular diseases: An overview of pre-clinical studies focused on the underlying molecular mechanism

C Fu, Y Li, H Xi, Z Niu, N Chen, R Wang, Y Yan… - Frontiers in …, 2022 - frontiersin.org
… In addition, collective evidence from these studies revealed that the cardiovascular toxicity
of … BaP exposure may affecte cardiovascular development and increased systolic blood …

Benzo [a] pyrene exposure influences the cardiac development and the expression of cardiovascular relative genes in zebrafish (Danio rerio) embryos

L Huang, C Wang, Y Zhang, J Li, Y Zhong, Y Zhou… - Chemosphere, 2012 - Elsevier
… time that PAH toxicity, including cardiac toxicity, is linked to … structure share a common toxic
mechanism mediated by the … cause early cardiac dysfunction during key stages of cardiac

[HTML][HTML] Mixture effects of oxygenated PAHs and benzo [a] pyrene on cardiovascular development and function in zebrafish embryos

V Cunha, C Vogs, F Le Bihanic, K Dreij - Environment International, 2020 - Elsevier
… developmental and cardiovascular toxicities induced by the … benzo[a]pyrene (BaP) either as
single exposures or binary oxy-… rescue of cardiovascular toxicity in ZFE exposed to 6H-BPO, …

Exposure to low dose benzo [a] pyrene during early life stages causes symptoms similar to cardiac hypertrophy in adult zebrafish

L Huang, D Gao, Y Zhang, C Wang, Z Zuo - Journal of hazardous materials, 2014 - Elsevier
exposure during early life stages to low dose benzo[a]pyrene (BaP), as a high-ring PAH,
would lead to cardiac … Zebrafish were exposed to low dose BaP until 96 hpf, then transferred to …

Cardiac toxicity of 5-ring polycyclic aromatic hydrocarbons is differentially dependent on the aryl hydrocarbon receptor 2 isoform during zebrafish development

JP Incardona, TL Linbo, NL Scholz - Toxicology and applied pharmacology, 2011 - Elsevier
… modes of toxic action for the 5-ring compounds benzo[a]pyrene (… An alternative explanation
is that cardiac toxicity in BkF-exposed … metabolic alteration resulting from BkF exposure. BkF …

… of the acute effects of benzo-a-pyrene on adult zebrafish (Danio rerio) cardiorespiratory function following intraperitoneal injection versus aqueous exposure

CJ Gerger, LP Weber - Aquatic Toxicology, 2015 - Elsevier
… Following acute BaP exposure, high frequency cardiac … BaP exposure has significant
sublethal toxicity in adult zebrafish. In particular, zebrafish aerobic capacity and cardiovascular

Early Exposure to Polycyclic Aromatic Hydrocarbons (PAHs) and Cardiac Toxicity in a Species (Xenopus laevis) with Low Aryl Hydrocarbon Receptor (AHR) …

MC Sestak, JA Pinette, CM Lamoureux, SL Whittemore - bioRxiv, 2018 - biorxiv.org
… Phenanthrene (PHE) and benzo(a)pyrene (BaP) are … toxicity, we compared the effects of
early exposure to the priority PAHs pyrene (PYR), fluoranthene (FLA), PHE and BaP on cardiac

[HTML][HTML] Benzo[a]pyrene—Environmental Occurrence, Human Exposure, and Mechanisms of Toxicity

B Bukowska, K Mokra, J Michałowicz - International journal of molecular …, 2022 - mdpi.com
… occurrence of B[a]P in various environmental compartments and human surroundings,
shows the exposure of humans to this substance, and describes the mechanisms of its toxicity. …

In utero exposure to benzo (a) pyrene predisposes offspring to cardiovascular dysfunction in later-life

GE Jules, S Pratap, A Ramesh, DB Hood - Toxicology, 2012 - Elsevier
… , the present study sought to survey the health implications of in utero B(a)P exposure
from the standpoint of developmental cardiovascular toxicity. The susceptibility-exposure