Risks of unbalanced progeny at amniocentesis to carriers of chromosome rearrangements: data from United States and Canadian laboratories
A Daniel, EB Hook, G Wulf - American journal of medical …, 1989 - Wiley Online Library
… fewer male than female carriers, whereas there were 1.3 times fewer male carriers in 2:2 …
carriers and risks of unbalanced progeny were found to be equal to those for female carriers, …
carriers and risks of unbalanced progeny were found to be equal to those for female carriers, …
[HTML][HTML] Translocations, inversions and other chromosome rearrangements
SJ Morin, J Eccles, A Iturriaga, RS Zimmerman - Fertility and sterility, 2017 - Elsevier
… for a carrier for pericentric inversion to have a child with an unbalanced chromosome
rearrangement is … chromosomal rearrangements resulting in viable offspring are rare (18). …
rearrangement is … chromosomal rearrangements resulting in viable offspring are rare (18). …
Familial complex chromosome rearrangement giving rise to balanced and unbalanced recombination products
L Zahed, V Der Kaloustian… - American journal of …, 1998 - Wiley Online Library
… mother is the carrier of a balanced complex 4-break chromosome rearrangement, which she
… to either a lower risk of producing abnormal progeny and, therefore, a lower probability of …
… to either a lower risk of producing abnormal progeny and, therefore, a lower probability of …
… balanced and unbalanced translocations as a consequence of a balanced complex chromosomal rearrangement involving eight breakpoints in four chromosomes
B Röthlisberger, D Kotzot, L Brecevic… - European journal of …, 1999 - nature.com
… offspring would be quite unlikely had to be revised after the birth of three children. Genetic
counselling of carriers of balanced complex rearrangements … report two unbalanced offspring …
counselling of carriers of balanced complex rearrangements … report two unbalanced offspring …
[HTML][HTML] … in adult carriers of a balanced chromosomal rearrangement ascertained in childhood: experiences from a nationwide reexamination of translocation carriers
I Bache, K Brondum-Nielsen, N Tommerup - Genetics in Medicine, 2007 - nature.com
… Purpose: Prenatal diagnosis is offered to carriers of a balanced chromosomal rearrangement
because it may predispose to offspring with an unbalanced karyotype. Therefore, carriers …
because it may predispose to offspring with an unbalanced karyotype. Therefore, carriers …
Reproductive risks for carriers of complex chromosome rearrangements: analysis of 25 families
JL Gorski, ML Kistenmacher, HH Punnett… - American journal of …, 1988 - Wiley Online Library
… carriers of complex chromosome rearrangements (CCRs). CCRs are structural rearrangements
involving at least three chromosomes … type of chromosomal imbalance in the offspring, …
involving at least three chromosomes … type of chromosomal imbalance in the offspring, …
Under‐ascertainment of mosaic carriers of balanced homologous acrocentric translocations and isochromosomes
NV Kovaleva, LG Shaffer - … Journal of Medical Genetics Part A, 2003 - Wiley Online Library
… offspring. Parents of fetuses and children with unbalanced homologous acrocentric
rearrangements … in most parents of offspring carrying homologous rearrangements prompted us to …
rearrangements … in most parents of offspring carrying homologous rearrangements prompted us to …
Balanced complex chromosome rearrangements: reproductive aspects. A review
K Madan - American Journal of Medical Genetics Part A, 2012 - Wiley Online Library
… carriers of a balanced complex chromosome rearrangement (… Eleven had one or more
offspring with an imbalance, ten by … ) resulting in unbalanced as well as balanced offspring. If one …
offspring with an imbalance, ten by … ) resulting in unbalanced as well as balanced offspring. If one …
“Balanced” karyotypes in six abnormal offspring of balanced reciprocal translocation normal carrier parents
SL Wenger, MW Steele, LY Boone… - American journal of …, 1995 - Wiley Online Library
… unbalanced affected offspring and 4 times as high as those seen in de novo cases. The
association of fragile sites with balanced rearrangements … might facilitate unequal crossing over …
association of fragile sites with balanced rearrangements … might facilitate unequal crossing over …
… of chromosomal abnormalities from preimplantation genetic testing to the reproductive outcomes: a comparison between three different structural rearrangements …
P Yuan, L Zheng, S Ou, H Zhao, R Li, HJ Luo… - Journal of Assisted …, 2021 - Springer
… but are associated with a high risk for unbalanced gametes and abnormal progeny. During
meiosis, the chromosomes of a carrier of a balanced reciprocal translocation pair must form a …
meiosis, the chromosomes of a carrier of a balanced reciprocal translocation pair must form a …