… new human gene, cbl-3, which encodes a protein with marked homology to the cbl family of
proteins… to the homology to the two known mammalian genes, we called this new gene cbl-3. …

… that the negative regulatory functions of Cbl proteins in PTK signaling are … mammals,
the Cbl family is composed of three members, Cbl (also known as c-Cbl), Cbl-b and Cbl-c (Cbl-3…

… Cbl-3 is the most recent mammalian cbl family member to be identified in humans (… Cbl-3
and utilize gene-targeted deletion of Cbl-3 to characterize the requirements for this protein in …

… Cbl is a ubiquitously expressed, primarily cytosolic protein. The mammalian Cbl family
consists of three genes c-cbl, cbl-b, and cbl-c/cbl-3. A large number of vertebrate and invertebrate …

… cloned a novel gene, cbl-c, of mammalian cbl-family. The … Cbl-c protein binds to the EGF
receptor and Fyn tyrosine kinase. We conclude that Cbl-c is a novel Cbl-family adaptor protein …

… Two members of the Cbl family have since been defined in mammals (c-Cbl and …
Homologues of mammalian Cbl proteins have been defined in C. elegans and Drosophila. The C. …

… In mammals, this family includes Cbl (also known as c-Cbl), Cbl-b and Cbl-c (also known
as Cbl-3 or Cbl-SL [7]). Extensive biochemical studies have demonstrated that they act …

… Finally, Chapter 9, written by Tohru Tezuka, Minsoo Kim and Tadashi Yamamoto, is focused
on Cbl-3/Cbl-c, the smallest and the least understood member of the mammalian Cbl family. …

… There are three mammalian Cbl proteins encoded by separate genes: Cbl (aka, c-… A, the
domain organization of the mammalian Cbl proteins. v-Cbl, the Gag-Cbl fusion protein of the …

… The mammalian Cbl family of proteins consists of three homologues known as c-Cbl, Cbl-b
and Cbl-3 (Figure 1). All three share highly conserved regions in their N-terminal halves …