The role of p38 MAP kinase in cancer cell apoptosis
M Lenassi, A Plemenitaš - Radiology and Oncology, 2006 - radioloncol.com
… Recently, it was observed that retinoids, cisplantin and also other chemoterapeutic agents
initiate cancer cell apoptosis through the activation of p38 MAP kinase. This finding connects …
initiate cancer cell apoptosis through the activation of p38 MAP kinase. This finding connects …
p38 MAPK in development and cancer
C Bradham, DR McClay - Cell cycle, 2006 - Taylor & Francis
… For example, p38 was shown to induce apoptosis in some cells, but prevent apoptosis in
others. … such as vinblastine, vincristine and taxol induce tumor cell apoptosis that is inhibited by …
others. … such as vinblastine, vincristine and taxol induce tumor cell apoptosis that is inhibited by …
p38 MAP kinase: a convergence point in cancer therapy
JM Olson, AR Hallahan - Trends in molecular medicine, 2004 - cell.com
… upstream of p38 MAPK. Here, we review p38-MAPK-mediated tumor cell apoptosis and …
However, it is difficult to assess the effect of p38 MAPK or p38 MAPK inhibitors on apoptosis …
However, it is difficult to assess the effect of p38 MAPK or p38 MAPK inhibitors on apoptosis …
p38 MAP kinase regulates stem cell apoptosis in human hematopoietic failure
L Zhou, J Opalinska, A Verma - Cell cycle, 2007 - Taylor & Francis
… p38 MAPK is overactivated in myelodysplasia bone marrows and regulates hematopoi‑ etic
stem cell apoptosis… Our results demonstrate that p38 MAPK is activated in bone marrow cells …
stem cell apoptosis… Our results demonstrate that p38 MAPK is activated in bone marrow cells …
Role of p38 mitogen-activated protein kinase (p38 MAPK) in cytokine-induced rat islet cell apoptosis
J Saldeen, JC Lee, N Welsh - Biochemical pharmacology, 2001 - Elsevier
… IFN-γ increased both apoptosis and necrosis in rat islet cells. … , partially prevented
cytokine-induced apoptosis, an effect that was … -induced p38 activation participates in β-cell …
cytokine-induced apoptosis, an effect that was … -induced p38 activation participates in β-cell …
Interplay between Akt and p38 MAPK pathways in the regulation of renal tubular cell apoptosis associated with diabetic nephropathy
MJ Rane, YE Song, S Jin, MT Barati… - American Journal …, 2010 - journals.physiology.org
… contributes to p38 MAPK-mediated RPTC apoptosis, fibrosis, … 1) whether Akt/p38 MAPK
expression/phosphorylation is … /p38 MAPK expression/phosphorylation and RPTC apoptosis are …
expression/phosphorylation is … /p38 MAPK expression/phosphorylation and RPTC apoptosis are …
p38 MAPK mediates γ-irradiation-induced endothelial cell apoptosis, and vascular endothelial growth factor protects endothelial cells through the phosphoinositide 3 …
P Kumar, AI Miller, PJ Polverini - Journal of Biological Chemistry, 2004 - ASBMB
… protected from γ-irradiation-induced apoptosis predominantly through the PI3K/Akt … cell
apoptosis predominantly via the activation of p38 MAPK, and VEGF protects endothelial cells …
apoptosis predominantly via the activation of p38 MAPK, and VEGF protects endothelial cells …
Tumor necrosis factor alpha induces neural stem cell apoptosis through activating p38 MAPK pathway
N Chen, F Wei, L Wang, S Cui, Y Wan, S Liu - Neurochemical research, 2016 - Springer
… underlying TNF-α-induced apoptosis in NSCs. Our research demonstrates the role of p38
MAPK as a novel apoptotic signal during TNF-α-induced apoptosis in NSCs. Moreover, our …
MAPK as a novel apoptotic signal during TNF-α-induced apoptosis in NSCs. Moreover, our …
Oxidative stress-induced intestinal epithelial cell apoptosis is mediated by p38 MAPK
Y Zhou, Q Wang, BM Evers, DH Chung - Biochemical and biophysical …, 2006 - Elsevier
… types, we sought to determine the exact role of p38 MAPK in the H 2 O 2 -… cell (RIE-1)
apoptosis. We show that H 2 O 2 induces apoptosis in RIE-1 cells with activation of p38 MAPK. …
apoptosis. We show that H 2 O 2 induces apoptosis in RIE-1 cells with activation of p38 MAPK. …
p38 MAPK mediates renal tubular cell TNF-α production and TNF-α-dependent apoptosis during simulated ischemia
KK Meldrum, DR Meldrum, KL Hile… - … of Physiology-Cell …, 2001 - journals.physiology.org
… As we develop a greater understanding of mediators of ischemia-induced renal cell
apoptosis, such as p38 MAP kinase, effective therapeutic strategies that limit or prevent ischemia-…
apoptosis, such as p38 MAP kinase, effective therapeutic strategies that limit or prevent ischemia-…
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