Immune checkpoint inhibitors: new insights and current place in cancer therapy
NM La‐Beck, GW Jean, C Huynh… - … and Drug Therapy, 2015 - Wiley Online Library
… lung cancer (NSCLC). We also compare and contrast their current place in cancer therapy
… discuss the role of dual immune checkpoint inhibition and strategies for the management of …
… discuss the role of dual immune checkpoint inhibition and strategies for the management of …
[HTML][HTML] Immune checkpoint inhibitors in cancer therapy
… medicine, and cancer therapeutics [1]. Immunotherapy such as adoptive cell transfer (ACT),
and immune checkpoint inhibitors (ICIs), is a type of cancer therapy, taking advantage of …
and immune checkpoint inhibitors (ICIs), is a type of cancer therapy, taking advantage of …
Immune checkpoint inhibitors for cancer therapy: clinical efficacy and safety
SC Azoury, DM Straughan… - Current cancer drug …, 2015 - ingentaconnect.com
… Immune checkpoints that have gained much attention over the past decade as targets for
cancer therapy include the co-inhibitory receptor programmed death-1 (PD-1, also known as …
cancer therapy include the co-inhibitory receptor programmed death-1 (PD-1, also known as …
Immune checkpoint inhibitors in cancer therapy: a focus on T‐regulatory cells
V Sasidharan Nair, E Elkord - Immunology and cell biology, 2018 - Wiley Online Library
… therapy with nivolumab and ipilimumab.116 In conclusion, it is critical to investigate the precise
mechanism of action of each checkpoint inhibitor … for a more successful cancer therapy. …
mechanism of action of each checkpoint inhibitor … for a more successful cancer therapy. …
[HTML][HTML] Immune checkpoint inhibitors in cancer therapy
ES Webb, P Liu, R Baleeiro, NR Lemoine… - Journal of biomedical …, 2018 - ncbi.nlm.nih.gov
… development of checkpoint inhibitors. This shifted the focus from developing therapies that
targeted activation of the host immune system against cancer to checkpoint inhibitors, which …
targeted activation of the host immune system against cancer to checkpoint inhibitors, which …
[HTML][HTML] Clinical impact of checkpoint inhibitors as novel cancer therapies
K Shih, HT Arkenau, JR Infante - Drugs, 2014 - Springer
… checkpoint inhibitors suggest these agents may have the potential to markedly improve
outcomes for patients with cancer. … encountered using these checkpoint inhibitors in the clinic. …
outcomes for patients with cancer. … encountered using these checkpoint inhibitors in the clinic. …
[HTML][HTML] Combining immune checkpoint inhibitors with conventional cancer therapy
Y Yan, AB Kumar, H Finnes, SN Markovic… - Frontiers in …, 2018 - frontiersin.org
… immunity, especially the identification of immune checkpoint pathways, has led to the …
a revolution in cancer therapy since the introduction of immune checkpoint inhibitors (ICIs), …
a revolution in cancer therapy since the introduction of immune checkpoint inhibitors (ICIs), …
Immune checkpoint blockade therapy for cancer: an overview of FDA-approved immune checkpoint inhibitors
KM Hargadon, CE Johnson, CJ Williams - International …, 2018 - Elsevier
… checkpoint inhibitors for cancer (Table 1), with emphasis on: 1) the ways in which ICB
regimens have already revolutionized cancer … checkpoint inhibitors as anti-cancer therapeutic …
regimens have already revolutionized cancer … checkpoint inhibitors as anti-cancer therapeutic …
[HTML][HTML] The role of immune checkpoint inhibitors in cancer therapy
AM Basudan - Clinics and Practice, 2022 - mdpi.com
… -L1), respectively, in the inhibition of negative immune regulation [6]. This review sheds light
on a specific class of immunotherapy called immune checkpoint inhibitors (CPIs). There are …
on a specific class of immunotherapy called immune checkpoint inhibitors (CPIs). There are …
[HTML][HTML] A decade of immune-checkpoint inhibitors in cancer therapy
C Robert - Nature communications, 2020 - nature.com
… -PD1 drugs for the highly mutated cancers linked to a mismatch DNA repair deficiency (microsatellite
instability) 8 . This is a rare example in the history of cancer therapy that a drug was …
instability) 8 . This is a rare example in the history of cancer therapy that a drug was …
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