Comparative analysis of the efficacy and safety of chemotherapy with oxaliplatin plus fluorouracil/leucovorin between elderly patients over 65 years and younger …

YH Cho, SY Kim, M Hong Lee, MW Yoo, HY Bang… - Gastric Cancer, 2012 - Springer
study has shown that the efficacy of chemotherapy with the mFOLFOX6 regimen among
elderly gastric cancer patients … efficacy among younger gastric cancer patients in terms of RR, …

Comparative effectiveness of chemotherapy in elderly patients with metastatic colorectal cancer

S Satram-Hoang, L Lee, S Yu, SR Guduru… - Journal of …, 2013 - Springer
… Comorbid health conditions and older age appear to influence … with older patients more
likely to receive shorter chemotherapy regimens with less toxicity [23–27]. The goal of this study

[PDF][PDF] Chemotherapy compliance, tolerance and efficacy in elderly and non-elderly patients with metastatic colorectal cancer: a single institution comparative study

M Bakogeorgos, G Mountzios, G Kotsantis… - J buon, 2013 - jbuon.com
analysis in a series of 94 mCRC patients. Using the cut-off of 70 years, we compared elderly
patients … (RDI), duration], chemotherapy toxicity and efficacy [objective response rate (ORR), …

Comparative analysis of azacitidine and intensive chemotherapy as front-line treatment of elderly patients with acute myeloid leukemia

L Maurillo, F Buccisano, A Spagnoli, MT Voso… - Annals of …, 2018 - Springer
… of this study suggest that AZA may be considered a valid alternative for older patients with …
and IC should rely on patient’s clinical and biological fitness, patients’ willingness, logistics (eg…

A retrospective analysis comparing the safety and efficacy of chemotherapy in elderly and non‐elderly non‐small‐cell lung cancer patients

Y Tsubata, T Honda, T Okimoto, K Miura… - Geriatrics & …, 2012 - Wiley Online Library
… to carry out a comparative analysis. In total, there were 64 non-elderly patients treated using
… In conclusion, the present retrospective study suggests that elderly patients should have the …

The impact of age on quality of life in breast cancer patients receiving adjuvant chemotherapy: a comparative analysis from the prospective multicenter randomized …

E Leinert, S Singer, W Janni, N Harbeck… - Clinical breast …, 2017 - Elsevier
… impact of chemotherapy on QoL in elderly patients is crucial. This study compared QoL in
patients aged < 65 years and 65 to 70 years receiving adjuvant chemotherapy as a secondary …

A comparative analysis of survival outcomes between pancreatectomy and chemotherapy for elderly patients with adenocarcinoma of the pancreas

S Marmor, EE Burke, BA Virnig, EH Jensen, TM Tuttle - Cancer, 2016 - Wiley Online Library
… In the current study of elderly patients, the median survival after surgery alone was 13
months compared with 16 months for those who received chemotherapy after surgery. …

Comparison of the efficacy and safety of single-agent and doublet chemotherapy in advanced non-small cell lung cancer in the elderly: a meta-analysis

G Des Guetz, B Uzzan, P Nicolas, D Valeyre… - Critical reviews in …, 2012 - Elsevier
… -agent chemotherapy among elderly patients aged 70 years or more. It also aimed to assess
the comparative efficacy and side effects of regimens including platinum derivates or not. …

Relative effectiveness and safety of chemotherapy in elderly and nonelderly patients with stage III colon cancer: a systematic review

A Hung, CD Mullins - The Oncologist, 2013 - academic.oup.com
… withholding treatment, elderly patients should receive chemotherapy as often as nonelderly
… was determined by comparing a reported estimate for elderly patients to a reported estimate …

Chemotherapy toxicity in older adults optimized by geriatric assessment and intervention: a non-comparative analysis

M Hamid, M Hannan, N Myo Oo, P Lynch, DJ Walsh… - Current …, 2022 - mdpi.com
… Our data show the vulnerability of older patients with cancer to the toxic effects of chemotherapy
and thus the importance of a multidisciplinary and tailored approach to each patient. …