[HTML][HTML] Chronic cerebrospinal venous insufficiency in multiple sclerosis: clinical correlates from a multicentre study
S Bastianello, A Romani, G Viselner, EC Tibaldi… - BMC neurology, 2011 - Springer
Background Chronic cerebrospinal venous insufficiency (CCSVI) has recently been reported
to be associated with multiple sclerosis (MS). However, its actual prevalence, possible
association with specific MS phenotypes, and potential pathophysiological role are debated.
Method We analysed the clinical data of 710 MS patients attending six centres (five Italian
and one Canadian). All were submitted to venous Doppler sonography and diagnosed as
having or not having CCSVI according to the criteria of Zamboni et al. Results Overall …
to be associated with multiple sclerosis (MS). However, its actual prevalence, possible
association with specific MS phenotypes, and potential pathophysiological role are debated.
Method We analysed the clinical data of 710 MS patients attending six centres (five Italian
and one Canadian). All were submitted to venous Doppler sonography and diagnosed as
having or not having CCSVI according to the criteria of Zamboni et al. Results Overall …
[HTML][HTML] Chronic cerebrospinal venous insufficiency in multiple sclerosis: a historical perspective
MD Dake, R Zivadinov, EM Haacke - Functional neurology, 2011 - ncbi.nlm.nih.gov
Chronic cerebrospinal venous insufficiency (CCSVI) is a term used to describe impaired
venous drainage from the central nervous system (CNS) caused by abnormalities in
anatomy and flow affecting the extracranial veins. Recently, it has been proposed that
CCSVI may contribute to the pathogenesis of multiple sclerosis (MS). It is hypothesized that
venous obstruction results in abnormal flow that promotes inflammation at the blood-brain
barrier and that this triggers a process marked by a disturbance of homeostasis within the …
venous drainage from the central nervous system (CNS) caused by abnormalities in
anatomy and flow affecting the extracranial veins. Recently, it has been proposed that
CCSVI may contribute to the pathogenesis of multiple sclerosis (MS). It is hypothesized that
venous obstruction results in abnormal flow that promotes inflammation at the blood-brain
barrier and that this triggers a process marked by a disturbance of homeostasis within the …