Clinical and genetic characterization of de novo double-hit B cell precursor leukemia/lymphoma

JA Stratmann, AB von Rose, S Koschade… - Annals of …, 2019 - Springer
… Here, we report the clinical and genetic characteristics of 6 cases of de novo acute B cell
precursor leukemia that harbored combined MYC and BCL2 and/or BCL6 rearrangements (DH/…

[HTML][HTML] Unique clinico-biological, genetic and prognostic features of adult early T-cell precursor acute lymphoblastic leukemia

E Genescà, M Morgades, P Montesinos, P Barba… - …, 2020 - ncbi.nlm.nih.gov
… survival of patients with or without early T-cell precursor acute lymphoblastic leukemia. (A)
Overall survival of adults with early T-cell precursor acute lymphoblastic leukemia (ETP-ALL) …

[HTML][HTML] Clinical and molecular characterization of early T-cell precursor leukemia: a high-risk subgroup in adult T-ALL with a high frequency of FLT3 mutations

M Neumann, S Heesch, N Gökbuget, S Schwartz… - Blood cancer …, 2012 - nature.com
… A subgroup of pediatric acute T-lymphoblastic leukemia (T-ALL) was characterized by a gene
… We have investigated clinical and molecular characteristics of the ETP-ALL subgroup in …

… heterogeneity of BCR/ABL+ adult B-cell precursor acute lymphoblastic leukemia: impact on the clinical, biological and immunophenotypical disease characteristics

D Primo, MD Tabernero, JJ Perez, A Rasillo… - Leukemia, 2005 - nature.com
Philadelphia-positive (Ph+) B-cell precursor acute lymphoblastic leukemia (BCP–ALL) is a
genetically heterogeneous disease with a very poor prognosis. In this study, we analyzed the …

[HTML][HTML] Clinical and molecular characterization of early T-cell precursor acute lymphoblastic leukemia: two cases report and literature review

XX Wang, D Wu, L Zhang - Medicine, 2018 - journals.lww.com
… The chromosomal analysis of the BM cells was 46,XY,?t(5;12)(q33;p13)[10]/46,XY. [10]
The fusion genes listed in Table 1 were all negative. For gene mutation analysis, DNMT3A …

Establishment and characterization of human B cell precursor-leukemia cell lines

Y Matsuo, HG Drexler - Leukemia research, 1998 - Elsevier
… Here, we have summarized the immunological, molecular and standard cytogenetic
features of a panel of well characterized B cell precursor (BCP)-leukemia cell lines which were …

Genomic and clinical characterization of early T-cell precursor lymphoblastic lymphoma

X Xu, CN Paxton, RJ Hayashi, KP Dunsmore… - Blood …, 2021 - ashpublications.org
… Genomic and gene expression studies have shown that T-LLy and T-ALL have different
transcriptional and genetic characteristics. For example, genes involved in chemotactic …

[PDF][PDF] Unique clinico-biological, genetic and prognostic features of adult early T cell precursor acute lymphoblastic leukemia

R Guàrdia, MJ Moreno, D Martínez-Carballeira… - 2019 - academia.edu
… of early T-cell precursor leukemia: a high-risk subgroup in adult T-ALL with a high frequency
… T-cell precursor ALL characterize a stem cell like leukemia and imply the clinical use of …

[HTML][HTML] Molecular basis and clinical significance of genetic aberrations in B-cell precursor acute lymphoblastic leukemia

F Ghazavi, T Lammens, N Van Roy, B Poppe… - Experimental …, 2015 - Elsevier
… Recent developments in genomewide genetic analysis have provided a wide range of
chromosomal and genomic abnormalities characterizing BCP-ALL, several of which are …

[HTML][HTML] Delineating human B cell precursor development with genetically identified PID cases as a model

MWJ Wentink, T Kalina, M Perez-Andres… - Frontiers in …, 2019 - frontiersin.org
… Identification and characterization of the different B-cell precursor (BCP) subsets contributes
to the understanding of normal B-cell development (3, 4). Currently, it is accepted that …